All news from Neurology

Marijuana Use Tied to Serious Diabetes Complication

People with type 1 diabetes who use marijuana may double their risk of developing a life-threatening complication, a new study suggests. Called diabetic ketoacidosis (DKA), the condition occurs when there is not enough insulin to break sugar in the body, so the body burns fat for fuel instead. This triggers a build-up of chemicals known as ketones, which make blood more acidic and can lead to coma or death

3D-Engineered Human Heart Tissue Beat

Researchers have developed a way to grow human heart tissue that can serve as a model for the upper chambers of the heart, known as the atria. The tissue, derived from human induced pluripotent stem cells (hiPCSs), beats, expresses genes, and responds to drugs in a similar manner to a real human atrium. The model may be useful for evaluating disease mechanisms and drugs for atrial fibrillation – the most common type of arrhythmia.

'Tunability' of a Molecular Chaperone

Scientists report that Hsp70s from mammalian cells behave quite differently from bacterial Hsp70s. Because of the important roles Hsp70s play in protein misfolding diseases such as cancer and neurodegenerative diseases, the new findings 'will have a major impact on how we think about Hsp70s,' one of the researchers says. The study appears in  PNAS.