A study commissioned to help guide revisions of best practices in providing palliative care finds that there is a wide and varied body of evidence to support such clinical practice guidelines. The study was published in the Journal of Pain and Symptom Management.
Think of the protein BH3 like a finger that turns off to cancer cell survival switch. The problem is that most cancer cells have found ways to remove this "finger commonly, by breaking the action of a gene called p53 that puts the BH3 finger in motion.
Now think of Bcl-2 as the switch itself. When cancer breaks p53, the BH3 finger never moves, and the Bcl-2 survival switch remains on. Despite thousands of published studies, researchers have not had much luck directly protecting the action of p53. But, BH3 is another story.
The study was published in the journal Cell Death and Disease.
Sudden cardiac death is a common cause of death in patients with congenital or acquired heart disease. An implanted cardiac defibrillator (ICD) can effectively put a stop to any underlying cardiac arrhythmia. In a long-term observational study involving 1,500 patients.
Researchers have shown that the progress selected for the implanted defibrillators (ICDs) plays a major role. It was found that the most "defensive" possible procedure is safe and, at the same time, significantly reduces inappropriate therapy.
The study was published in Circulation.
Researchers have discovered a new structure in human cells. The structure is a new type of protein complex that the cell uses to attach to its surroundings and proves to play a key part in cell division. The study was published in the journal Nature Cell Biology.
Researchers have discovered how the frontline Type 2 diabetes drug metformin may work to help cells better take up and use glucose. They may also explain other potentially beneficial effects of metformin the for prevention of a variety of chronic diseases, including cancers. The study was published today in the prestigious journal Cell.
Men who lack resilience are exponentially more vulnerable to becoming severely depressed after their spouse dies, according to a new study from Florida State University researchers.
Final results of a clinical trial show continued evidence that women who get injections of the hormone drug goserelin along with standard breast cancer chemotherapy are more likely to become pregnant – without developing negative side effects or shortening their lives.
Prime Minister Narendra Modi's flagship health insurance scheme 'Ayushman Bharat' has been merged with the Mamata Banerjee government's 'Swasthya Sathi' scheme in West Bengal, family people with the development said.
Bhutanese voters have given a decisive mandate to the Druk Nyamrup Tshogpa (DNT) in the just-concluded third round of the country's third general elections. A new party, established only in 2013, the DNT secured 54% of the votes and won 30 of the 47 seats in the National Assembly. With 17 seats, runner-up Druk Phuensum Tshogp heartening that they are expressing their support for change via the ballot box.
Insufficient evidence exists to demonstrate that monotherapy with correctors has clinically important effects in individuals with cystic fibrosis (CF) who have 2 copies of the F508 of the mutation, according to an analysis published in the Cochrane Database of Systematic Reviews.
Teenagers with HIV and their families can improve care about health care goals when advance care planning is discussed with a doctor early in the course of treatment, according to research published in Pediatrics. This agreement, according to the researchers, can reduce HIV symptoms and suffering for the patient.
Aspergillus is an important fungal genus, with roles in agriculture, biotechnology, human health, enzyme production and food fermentation. Scientists now present the first large analysis of an Aspergillus fungal subgroup, section Nigri.