Patients treated with more-invasive surgical techniques for a type of early-stage lung cancer are more likely to become chronic opioid users than patients treated with minimally invasive surgery, highlighting the need for additional research into how pain management after surgery might be a contributing factor to the opioid addiction crisis, according to a study published in JAMA Oncology.
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Scientists have been able to grow human esophageal tissue entirely from pluripotent stem cells (PSCs), which can form any tissue type in the body. Scientists working to bioengineer the entire human gastrointestinal system in a laboratory now report using pluripotent stem cells to grow human esophageal organoids. The study was published in the journal Cell Stem Cell.
Sixty-year-old Emma Zhakata winces, struggling to hold back tears as she relates how her husband, one of 32 cholera victims in Zimbabwe, died within hours of falling ill. She never suspected her 69-year-old husband, Wonder Zhakata, would die suddenly after complaining that he felt weak and was suffering stomach pain.
A protein's folding patterns help them perform their dedicated tasks. As the real "doers" of the cell, even a tiny alteration in a protein's amino acid backbone can cause misfolding and hinder the protein's functionality or cause disease.
For instance, if tau, a protein that helps stabilize the structure of brain cells, is misfolded, it can form tau-tangles, which are commonly seen in Alzheimer's patients. Scientists seek to better understand protein folding to cure misfolding diseases, but this incredibly complex process requires sophisticated algorithms to identify the folding mechanisms.
They have proposed a new way to identify the most crucial factors for protein folding. They demonstrated the short simulation time of their approach on a small but intriguing protein, GB1 beta-hairpin. The study was published in the Journal of Chemical Physics.
Intestinal bacteria can create an electric current, according to a new study. The results are valuable for the development of drugs, but also for the production of bioenergy, for example.
Researchers used advanced microscopes to determine at atomic resolution the structure of a molecular complex implicated in birth defects and several cancers. The study was published today in Science.
The weight-based dosing of ondansetron to reduce hypotension has never been investigated. The aim of this study is to determine the optimal dose of ondansetron required based on the patient's weight to reduce hypotension following spinal anesthesia for cesarean section.
The University of Birmingham has been awarded £1.9 million through the National Institute for Health Research (NIHR) Global Health Research (GHR) Program to fund world-class research into a common heart condition in disadvantaged populations in China, Brazil, and Sri Lanka.
You laugh. You cry. You love. And you lose. It is nearly impossible, to sum up, the range of emotions felt each day within the walls of Barrie’s 10-bed Hospice, Simcoe. In only a few short hours spent touring the facility and engaging with residents a few weeks ago, Simcoe.com sat in on a birthday singalong and watched a daughter hold her dying father’s hand for a casting mold. There is laughter in the kitchen and silence in a room where a resident has just died.
Powdered protein supplements are one of the most commonly consumed nutritional supplements, whether by professional sportspeople or amateurs, even by those who use them for aesthetic purposes instead of sporting ones. This study research team has analyzed the quality of these products in function of their source, treatment, and storage.
A novel therapy technique invented by researchers at The University of Texas at Dallas has been shown in a pilot study to double the rate of upper limb recovery in stroke patients, a leap forward in treating the nearly 800,000 Americans who suffer strokes each year. The study was published in the journal Stroke.