All news from Anaesthesiology

Invasive Lung Cancer Surgery Lead to Long-term Opioid Use, Findings

Patients treated with more-invasive surgical techniques for a type of early-stage lung cancer are more likely to become chronic opioid users than patients treated with minimally invasive surgery, highlighting the need for additional research into how pain management after surgery might be a contributing factor to the opioid addiction crisis, according to a study published in JAMA Oncology

Pluripotent Stem Cells To Grow Human Esophageal Organoids

Scientists have been able to grow human esophageal tissue entirely from pluripotent stem cells (PSCs), which can form any tissue type in the body. Scientists working to bioengineer the entire human gastrointestinal system in a laboratory now report using pluripotent stem cells to grow human esophageal organoids. The study was published in the journal Cell Stem Cell.

Cholera Outbreaks: Fear and Anger Strikes Again in Zimbabwe

Sixty-year-old Emma Zhakata winces, struggling to hold back tears as she relates how her husband, one of 32 cholera victims in Zimbabwe, died within hours of falling ill. She never suspected her 69-year-old husband, Wonder Zhakata, would die suddenly after complaining that he felt weak and was suffering stomach pain. 

Chaperones Prepare Proteins For Folding By Their Own

A protein's folding patterns help them perform their dedicated tasks. As the real "doers" of the cell, even a tiny alteration in a protein's amino acid backbone can cause misfolding and hinder the protein's functionality or cause disease.

For instance, if tau, a protein that helps stabilize the structure of brain cells, is misfolded, it can form tau-tangles, which are commonly seen in Alzheimer's patients. Scientists seek to better understand protein folding to cure misfolding diseases, but this incredibly complex process requires sophisticated algorithms to identify the folding mechanisms.

They have proposed a new way to identify the most crucial factors for protein folding. They demonstrated the short simulation time of their approach on a small but intriguing protein, GB1 beta-hairpin. The study was published in the Journal of Chemical Physics.

Hospice Care To Those In Need Of Health Care

You laugh. You cry. You love. And you lose. It is nearly impossible, to sum up, the range of emotions felt each day within the walls of Barrie’s 10-bed Hospice, Simcoe. In only a few short hours spent touring the facility and engaging with residents a few weeks ago, sat in on a birthday singalong and watched a daughter hold her dying father’s hand for a casting mold. There is laughter in the kitchen and silence in a room where a resident has just died.

Enhance Rehab For Stroke Doubles Movement Recovery

A novel therapy technique invented by researchers at The University of Texas at Dallas has been shown in a pilot study to double the rate of upper limb recovery in stroke patients, a leap forward in treating the nearly 800,000 Americans who suffer strokes each year. The study was published in the journal Stroke.