New work could provide sustainable ways to make chemicals, medicines, and biomaterials. Single-pot Glycoprotein Biosynthesis Using a Cell-Free Transcription-Translation System Enriched with Glycosylation Machinery, the study was published in Nature Communications.
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Researchers are reporting how they used cryo-EM to show the structure of a version of a virus called an AAV2, advancing the technique's capabilities and the virus' potential as a delivery vehicle for gene therapies. The study was published in Nature Communications.
Selective Inhibition Reverses Hyperexcitability Of Peripheral Nociceptors & Alleviates Postsurgical Pain
Researchers have published a study that improves the understanding of the pain-sensing neurons that respond to tissue injury during surgery. The study was published in the journal Science Signaling. They investigated the potential role and molecular mechanisms of nociceptive ion channel dysregulation in acute pain conditions such as those resulting from the skin and soft tissue incision.
A team of researchers are gathering bacteria from across the world to create a microbiota vault that would preserve the myriad of strains of bacteria that inhabit the human gut and other mucosal levels.
Veracyte, Inc. announced the presentation of data demonstrating that the Envisia Genomic Classifier can help physicians more confidently diagnose interstitial lung disease (ILD), including idiopathic pulmonary fibrosis (IPF), without the need for surgery. The data were shared in an oral presentation at CHEST 2018, the annual meeting of the American College of Chest Physicians®, which is being held October 6-10 in San Antonio, Texas.
Smoke inhalation, pneumonia, and combat-related trauma are just a few causes of acute respiratory distress syndrome, a condition where the lungs fill with fluid, and is too often fatal. To help these critically ill patients, doctors use extracorporeal life support – a cardiopulmonary bypass system that artificially re-oxygenates blood when the lungs are too damaged to breathe normally.
Bacteria which 1 in 10 pregnant women carry, and which can cause death or serious complications in their babies, could be targeted in a cost-effective way by a future vaccine – even if it costs the NHS as high as £54 a dose.
The key to beating cancer could be growing plants in space, suggests new research. Plants have been found to release different chemicals when cultivated in zero gravity, offering hope of finding cures for a host of diseases from Alzheimer's to cystic fibrosis.
Melanoma is a deadly type of skin cancer that arises from pigment-forming cells. The article challenges the field by addressing provoking questions in melanoma immunotherapy, cancer systems biology, medical and surgical oncology, pigment biophysics, and precision prevention of skin diseases such as melanoma. The study was published in Pigment Cell & Melanoma Research article, world-leading experts identify emerging frontiers in skin cancer and pigment diseases.
With flu season nearly upon us, a new study looks at the factors behind the extremely high mortality of the 1918 flu pandemic and how to prepare for future outbreaks. The authors warn that while the world is better prepared than 100 years ago, new challenges will affect the impact of the next influenza virus pandemic — including changing population demographics, antibiotic resistance and climate change.
Scientists have discovered the role of an immune system double agent. This molecule, called USP18, can help curtail immune responses, but it can also open the door to bacterial infections, such as harmful listeria and staph infections. The study is published in the journal Science Immunology.
Data from a clinical trial has shown that how people respond to treatment for Bipolar Disorder may be influenced by their weight and the overall quality of their diet, including whether they are eating a diet high in foods thought to contribute to general inflammation.
These are early results, but if replicated may mean that treatment of some mental health problems could benefit from the inclusion of dietary advice. This is presented at the ECNP Conference in Barcelona.