When it comes to disorders affecting sleep, sleep apnea ranks on top with an estimated 936 million people worldwide suffering from the condition, the latest study has suggested. Sleep apnea is a chronic sleep-disordered breathing condition associated with increased risk of mortality and reduced quality of life.
Researchers found that women with the highest levels of the hormone, although still in the normal range, had a 27% reduced risk of developing type 2 diabetes compared to those with the lowest levels in the normal range.
Prolactin is a multi-function hormone-it is not only related to pregnancy and breastfeeding, but it also plays an important role in many other biological functions, like metabolism, immune regulation, and water balance. The study was published in the Diabetologia.
Schizophrenia is an extremely variable psychiatric disorder that is diagnosed based on the presence of specific symptoms. Thomas Wolfers and André Marquand of Radboud university medical center investigated how much the brains of individual patients diagnosed with schizophrenia differ from the 'average' patient.
For this purpose, they compared brain scans of 250 healthy individuals with those of 218 individuals with schizophrenia. Those with schizophrenia as a group differed from the healthy individuals in frontal brain regions, the cerebellum, and the temporal cortex. The study was published in JAMA Psychiatry.
Yale has developed a way to target RNA with small-molecule drugs, creating a new method for tapping into a vast number of biological mechanisms critical to metabolism and gene expression.
"There is tremendous interest in targeting RNA with small molecules," said Yale biochemist Anna Pyle, whose lab conducted the research. Despite this potential, there has been limited progress on the development of small-molecule drugs that bind RNA, and a pervasive view that RNA is not a viable therapeutic target.
A survey undertaken by the Bone Cancer Research Trust (BCRT) has revealed a diagnosis of breast cancer patients. The survey of 394 primary bone cancer patients, survivors, and bereaved families showed that one in four patients (26%) had waited over seven months before receiving a diagnosis with 13% waiting over a year
Lower back pain happens to millions of Americans every year, and back pain is caused by a number of reasons. If your back pain keeps coming back and it's not because of your mattress it's wrong for you-it might be time to investigate if something more serious is causing the problem
Researchers have developed designer molecules that may one day be able to seek out and trap deadly nerve agents and other toxic compounds in the environment – and possibly in humans.
New research highlights a more accurate way to screen for preeclampsia in pregnant women than currently recommended methods. Published early online in Ultrasound in Obstetrics & Gynecology, the study challenges the UK's current guidelines on the management of hypertensive disorders during pregnancy.
A new study led by investigators at Brigham and Women's Hospital and Harvard THR Chan School of Public Health is the first to look at the results of the black men and to whether an optimized screening strategy with baseline prostate-specific antigen (PSA) levels predict prostate cancer in this population
A new study evaluates important aspects of psychological health in young adults with kidney failure. The findings, which appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), point to the need for additional efforts to address the wellbeing of these patients
According to recent research, endurance exercise training beneficially modifies gut microbiota composition. After six weeks of training, potentially inflammation causing microbes (Proteobacteria) decreased and microbes that are linked to enhanced metabolism (Akkermansia) increased.
Mistakes in "proofreading" the genetic code of retinal cells is the cause of a form of inherited blindness, retinitis pigmentosa (RP) caused by mutations in splicing factors. This new understanding of the disease process, published in Nature Communications, is leading to the development of a gene therapy for RP caused by splicing factor defects.