All news from ENT

Sleep Apnea Condition Disturbing Night Sleep

When it comes to disorders affecting sleep, sleep apnea ranks on top with an estimated 936 million people worldwide suffering from the condition, the latest study has suggested. Sleep apnea is a chronic sleep-disordered breathing condition associated with increased risk of mortality and reduced quality of life.

Serum Prolactin In Pregnancy Predicts Prediabetes

Researchers found that women with the highest levels of the hormone, although still in the normal range, had a 27% reduced risk of developing type 2 diabetes compared to those with the lowest levels in the normal range.

Prolactin is a multi-function hormone-it is not only related to pregnancy and breastfeeding, but it also plays an important role in many other biological functions, like metabolism, immune regulation, and water balance. The study was published in the Diabetologia.

Differences In Brain Structure Among Patients With Schizophrenia

Schizophrenia is an extremely variable psychiatric disorder that is diagnosed based on the presence of specific symptoms. Thomas Wolfers and André Marquand of Radboud university medical center investigated how much the brains of individual patients diagnosed with schizophrenia differ from the 'average' patient.

For this purpose, they compared brain scans of 250 healthy individuals with those of 218 individuals with schizophrenia. Those with schizophrenia as a group differed from the healthy individuals in frontal brain regions, the cerebellum, and the temporal cortex. The study was published in JAMA Psychiatry.

Attacking RNA With Small-Molecules Drugs

Yale has developed a way to target RNA with small-molecule drugs, creating a new method for tapping into a vast number of biological mechanisms critical to metabolism and gene expression.

"There is tremendous interest in targeting RNA with small molecules," said Yale biochemist Anna Pyle, whose lab conducted the research. Despite this potential, there has been limited progress on the development of small-molecule drugs that bind RNA, and a pervasive view that RNA is not a viable therapeutic target.

Survey Uncovers Delay In Diagnosing Bone Cancer

A survey undertaken by the Bone Cancer Research Trust (BCRT) has revealed a diagnosis of breast cancer patients. The survey of 394 primary bone cancer patients, survivors, and bereaved families showed that one in four patients (26%) had waited over seven months before receiving a diagnosis with 13% waiting over a year