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Clinical Trials of Functional Engineered Oesophagus In-Process

The world's first functional oesophagus engineered from stem cells has been grown and successfully transplanted into mice, as part of a pioneering new study led by UCL. It was hoped this research, carried out by UCL Great Ormond Street Institute of Child Health (ICH), in collaboration with Great Ormond Street Hospital (GOSH) and the Francis Crick Institute, could pave the way for clinical trials of lab-grown food pipes for children with congenital and acquired gut conditions.

Severity of Asthma Symptoms Linked to Excessive Airway Nerves, Study

A new study implicates the remodeling of nerves in the airways as a key contributor to heightened sensitivity and airway constriction in patients with asthma. The results provide new insight into a little-understood factor in the development of asthma, a condition that affects about 235 million people worldwide. The study is the first to demonstrate that inflammatory cells can alter nerve structure in the lungs to cause disease.