Scientists at Mount Sinai have developed a novel technology for simultaneously analyzing the functions of hundreds of genes with resolution reaching the single cell level. The technology relies on a barcoding approach using a novel protein described in a paper published in the journal Cell
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A comprehensive new review article presents the most current understanding of the role selective serotonin reuptake inhibitors (SSRIs) play in the increased risk of multiple diverse gestational malformations and takes aim at the ongoing debate over whether SSRIs as a drug class can cause these malformations
India has world's third-highest number of billionaires. But at the same time, hidden hunger – micro-nutrient deficiency – continues to be a major public health issue. Today, India has an astounding 190 million undernourished people , the highest in the world. About 47.5 million Indian children under-5 years are stunted -again, the most in the world.
The Asian Development Bank's (ADB) Board of Directors has approved a $20 million grant financing package to support the efforts of the Government of Bhutan to improve the equity, efficiency, and sustainability of the country's health system.
How long a person with obstructive sleep apnea (OSA) stops breathing may be a better predictor of mortality risk from OSA than the number of times they stop breathing, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.
According to an online survey, although healthcare providers (HCPs) report sharing crucial information on bacterial vaginosis (BV) with patients, the associated risks of the condition remain a mystery to many women, indicating a significant disconnect. With BV known to be the most prevalent gynecologic infection in the U.S., affecting 21 million women each year, it's clear that further education is needed to bridge this gap in communication and help women to obtain diagnosis and treatment initiation sooner.
Biochemists, microbiologists, drug discovery experts, and infectious disease doctors have teamed up in a new study that shows antibiotics are not always necessary to cure sepsis in mice. Instead of killing causative bacteria with antibiotics, researchers treated infected mice with molecules that block toxin formation in bacteria. Every treated mouse survived. The breakthrough study, published in Scientific Reports, suggests infections in humans might be cured the same way.
Some bacterial pathogens, including those that cause strep throat and pneumonia, are able to create the components necessary to replicate their DNA without the usually required metal ions. This process may allow infectious bacteria to replicate even when the host's immune system sequesters iron and manganese ions in an attempt to slow pathogen replication.
A new study, which appears in the journal Proceedings of the National Academy of Science, describes a novel subclass of metal-free ribonucleotide reductase enzymes used by these bacteria, an understanding of which could drive the development of new, more effective antibiotics.
Since 2017, Olympus Corporation has participated in a joint research program that has the potential to help streamline the workload of clinical pathologists, called "A New Approach to Develop Computer-Aided Diagnosis Using Artificial Intelligence (AI) for Gastric Biopsy Specimens" with Dr. Kiyomi Taniyama, President of the Kure Medical Center and Chugoku Cancer Center.
Researchers developed a novel DNA influenza vaccine based on four micro-consensus antigenic regions selected to represent the diversity of seasonal H3N2 viruses across decades. The DNA vaccine protected mice against a lethal challenge with more than one influenza-A H3N2 virus.
It also protected them from severe H3N2-related illness despite the lack of an exact sequence match between the vaccine immunogen and H3 immunogen. The findings are reported in a new Special Issue on DNA Vaccines in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.
Mosquitoes are the world's deadliest animals, killing thousands of people and causing millions of illnesses each year. To be able to reproduce and become effective disease carriers, mosquitoes must first attain optimal body size and nutritional status. Study results appear in the Proceedings of the National Academy of Sciences.
Omega-3 fatty acids, such as those typically contained in fish oil, may suppress the growth and spread of breast cancer cells in mice. This is according to a new study in the journal Clinical & Experimental Metastasis, which is published under the Springer imprint.