All news from Anaesthesiology

Ethicon Demonstrates Life-Changing Obesity Treatment

Ethicon, part of Johnson & Johnson Medical Devices Companies (JJMD), demonstrates its commitment to improving access to life-changing obesity treatment and putting the most appropriate surgical tools in surgeons hands at the 23rd World Congress of the International Federation for the Surgery of Obesity and Metabolic Diseases (IFSO 2018).

Structure Of The Human Epithelial Sodium Channel By Cryo-EM

New research for the first time reveals the three-dimensional structure of a membrane channel that's critical in controlling blood pressure. The findings represent the first time the human epithelial sodium channel has been shown so precisely since it was first isolated and described through expression cloning more than two decades ago.

The breakthrough could lead to 'new and better treatments blood pressure medications. The study was published in the journal eLife.

Diseased Heart Muscle Cells Have Short Telomeres

Researchers say the finding could lead to new pathways for drug discovery. People with cardiomyopathy have abnormally short telomeres in the muscles that contract the heart. A telomere is a DNA sequence that serves as a protective cap on the ends of chromosomes.

A previous study showing that people with Duchenne muscular dystrophy, a genetic muscle-wasting disease, also have short telomeres in their heart muscle cells or cardiomyocytes. These patients often die at an early age from heart failure. The study was published in the Proceedings of the National Academy of Sciences.

Chaperones Convert The Energy Into The Nonequilibrium Stabilization Of Native Proteins

Chaperones are specialized proteins in the cell that help other proteins to reach their functional 3D shapes, which correspond to the states preferred at thermodynamic equilibrium. But a new study by EPFL, UNIL and INSERM (France) scientists shows that chaperones can also maintain proteins in non-equilibrium states, potentially altering their fate. The study was published in Nature Chemical Biology.

Sedation Is Unnecessary For Colonoscopy

Deep sedation for routine colonoscopy is of marginal benefit, costs more and may negatively affect safety and quality compared with mild-to-moderate sedation with traditional sedatives. The increasing use of deep sedation for colonoscopy in North America is a trend that should be curtailed to reduce unnecessary spending associated with procedures, and needless intervention that may cause harm.

In many countries, a large proportion of colonoscopies are performed with little or no sedation. According to a national audit in the United Kingdom, 0.4% of colonoscopies were performed using propofol, a short-acting drug that induces a state of deep sedation, and 10.7% were performed without sedation.
 

Australia Has Growing With Palliative Care Services

Australia has a growing and aging population, with palliative care services around the country busier than ever. It's provided almost anywhere that health care is available, including neo-natal units, acute hospitals, and aged care homes.

And what is on offer compares pretty well globally, according to those in the industry. Cancer Council Australia CEO Sanchia Aranda told PM although there was less home palliative care available in Australia than in the UK, we do better than the United States.

Critically Ill Delirium A Growing Concern

Since intensive-care units (ICU) were created in hospitals more than a half a century ago, there’s been a steady decline in death rates for individuals who are critically ill and require life support.

That’s significant and meaningful progress, and it’s thanks to the pioneering work of doctors, nurses and researchers who have discovered better ways to liberate patients from life support so they can leave the hospital functioning on their own.

Astronauts Risk Of Kidney Stones In Space Reduced By Ultrasonic Management

Bone demineralization, dehydration, and stasis put astronauts at an increased risk of forming kidney stones in space. The incidence of kidney stones and the potential for a mission-critical event are expected to rise as expeditions become longer and immediate transport to Earth becomes more problematic.

At the University of Washington, we are developing an ultrasound-based stone management system to detect stones with S-mode ultrasound imaging, break stones with burst wave lithotripsy (BWL), and reposition stones with ultrasonic propulsion (UP) on Earth and in space.

This review discusses the development and current state of these technologies, as well as integration on the flexible ultrasound system sponsored by NASA and the National Space Biomedical Research Institute.

Relationship Between Iron Deficiency And Hearing Loss

The body needs the right nutrients in the right amounts to support its overall function and to ensure that everything is working as it should. But is it possible that the deficiency of one important nutrient can put you at risk for hearing loss. According to researchers, iron deficiency and anemia during childhood may affect your hearing later in life.

The study was published in JAMA Otolaryngology-Head and Neck Surgery and followed 305 339 adults between the ages of 21 and 90.