A Phase 1 clinical trial examining whether a topical cream can enhance the immune response conferred by a 'pre-pandemic' influenza vaccine is underway. Investigators are evaluating whether imiquimod cream, commonly used to treat genital warts and certain skin cancers, can boost the body's immune response to an H5N1 influenza vaccine. The trial is enrolling 50 healthy adults ages 18-50 years.
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According to a new study, California's health profile was significantly better than the nation's as a whole — a profile largely driven by the state's minority population.
Currently available vaccines for the prevention of seasonal influenza virus infection have limited ability to induce immunity against diverse H3N2 viruses, an influenza A subtype that has led to high morbidity and mortality in recent years. Now, scientists have engineered a synthetic DNA vaccine shown to produce broad immune responses against these H3N2 viruses.
The parasitic disease leishmaniasis is spread to humans through the bites of sandflies, and is endemic in a number of countries, including Brazil. Despite control efforts, the incidence of visceral leishmaniasis — the most severe form of the disease — rose in Brazil between 1990 and 2016, researchers have reported in PLOS Neglected Tropical Diseases.
Several new medicines have been found to be more effective than traditional ones used to treat multidrug-resistant tuberculosis (MDR-TB), according to a new international collaborative study led by Dr. Dick Menzies, senior scientist. These findings precipitated a complete overhaul of worldwide TB treatment guidelines, with the results of this work published today in the British medical journal The Lancet.
A new wirelessly-powered light-emitting device, which sticks onto animal tissue like a sticker with tissue-adhesive and elastic nanosheets, could possibly facilitate treatment for hard-to-detect microtumors and deeply located lesions that are hard to reach with standard phototherapy.
If clinically applied, the device could be beneficial for cancer patients who seek minimally invasive treatment, helping them live longer and improve their quality of life.
In a recent study, researchers found that cows are a source of resistant staphylococcus strains causing infections in humans. The MRSA staphylococcus is an example of a pathogen, the likes of which are often called superbugs. These are resistant to most antibiotics and can cause serious infections.
Active top-flight athletes who have experienced sexual or physical abuse at some time in their life run a greater risk of sports-related injury. A new study has shown an association between lifetime abuse experience and injury risk in female athletes. The study is published in the British Journal of Sports Medicine.