All news from Anaesthesiology

Measuring the Activation of Receptors SpeedsDrug Devlopment, Findings

Researchers have developed a method that makes it possible to measure the activation of receptors in a very short time. This might speed up the development of new drugs.Hormones and other neurotransmitters, but also drugs, act upon receptors. "Their active substances bind to the receptors and modify the three-dimensional receptor arrangement regulating the downstream signal pathways," says Hannes Schihada.

'Hibernating' HIV Strains: Novel way for Dating

Researchers at the BC Centre for Excellence in HIV/AIDS (BC-CfE) and Simon Fraser University (SFU), in partnership with University of British Columbia (UBC) and Western University, have developed a novel way for dating "hibernating" HIV strains, in an advancement for HIV cure research in the province.

Published in Proceedings of the National Academy of Sciences (PNAS), the BC-CfE's first major scientific contribution to the area of HIV cure research confirms that dormant HIV strains can persist in the body for decades.

Zika Virus Proteins with Potential to Affect Brain Development, Findings

In healthy individuals, the Zika virus causes flu-like symptoms. If a pregnant woman becomes infected, the unborn child can suffer from severe brain abnormalities as a result of mechanisms that have not yet been explained. A study by the Technical University of Munich (TUM) and the Max Planck Institute of Biochemistry (MPI-B) shows that Zika virus proteins bind to cellular proteins that are required for neural development.

HIV and TB Epidemics: Researchers Work Towards its Prevention and Cure

Currently, South Africa has the largest number of people living with HIV in the world and is also experiencing a dramatically expanded tuberculosis epidemic. These two epidemics are tightly linked, as HIV increases TB risk and disease, and TB is the leading cause of death among people living with HIV. In 2002, the Yale AIDS Program began addressing the twin epidemics in KwaZuluNatal, the country's most populous and heavily burdened province.