The watchdog group Public Citizen is calling for the immediate end to a phase 3 National Institutes of Health (NIH) trial testing two treatments for sepsis, citing "serious ethical and regulatory lapses related to the design and sample consent."
Frail female nursing home residents who undergo breast cancer surgery suffer high rates of mortality and hospital readmission, as well as loss of functional independence, a study of US nursing home data that spans more than a decade has revealed.
Patient satisfaction after plastic surgery is most affected by surgeon-related factors, such as taking the time to answer questions and including patients in the decision-making process, reports a study in the September issue of Plastic and Reconstructive Surgery®.
Earlier this year, the American Cancer Society (ACS) updated its guidelines for colorectal cancer (CRC) screening and recommended that screening begins at age 45 for those at average risk for the disease.
The adult critical care unit at the University Hospitals of Morecambe Bay NHS Trust was over maximum safe capacity at the end of June, according to NHS England. critical care beds in the unit were occupied. Guidelines recommend that units run at no more than 85% capacity any higher and they say patient safety could be compromised. The Faculty of Intensive Care Medicine (FICM) has warned that many units across the country are either experiencing or approaching a ‘capacity crisis’.
Researchers have developed a novel tool for determining the sensitivity of bone healing to inhibition of the Wnt signaling pathway and have validated its use in a study of bone regeneration in mice. The tool, which is based on a lentivirus encoding a ß-catenin shRNA model, is described in an article published in Tissue Engineering.
The DNA in the cell nucleus is highly condensed, and genes must be rendered accessible before they can be activated. A team has now described the action of a protein complex that serves as a yardstick to measure lengths of exposed DNA. The new findings have just been published in the journal Nature Structural & Molecular Biology.
The technique puts patients in a 'sleepy' state but doesn't render them unconscious. TWILIGHT sedation is a medical term you may have heard of, but probably know little about. Here's the lowdown on the method, what it feels like when you're under the anesthetic and when it's used.
NASA is sending sperm cells into space in the hopes to investigate whether a conception of a human life is possible in a zero-gravity environment. The American space agency is moving one step forward in space exploration as the Micro-11 mission carries frozen human and bull sperms aboard the SpaceX Falcon 9.
In a statement, NASA said the scientists are studying the effects of weightlessness on the sperms' ability to fertilize the egg, which is a crucial stage in conception. Previous experiments with sea urchin and bull sperm suggest that activating movement happens more quickly in microgravity, while the steps leading up to fusion happen more slowly, or not at all. Delays or problems at this stage could prevent fertilization from happening in space.
According to a study, researchers estimated that single-step nasal spray naloxone is the easiest to deliver. Expanded access to naloxone, also known as Narcan®, has been identified as a key intervention for reducing opioid-related deaths. However, there is more than one way to administer it and it is unknown which method is most successful when as by community members.
Physician-researchers with The Ohio State University College of Medicine at the Wexner Medical Center say increased levels of the hormone aldosterone, already associated with hypertension, can play a significant role in the development of diabetes, particularly among certain racial groups.
This research is an important step toward finding new ways to prevent a major chronic disease. This shows how our diabetes and metabolism scientists are focused on creating a world without diabetes. The study was published in the Journal of the American Heart Association.
A study examined that combination therapy with halobetasol propionate 0.01%/tazarotene 0.045% (HP/TAZ) lotion in patients with moderate to severe plaque psoriasis provides a sustained treatment effect after 8 weeks of therapy and a 4-week posttreatment period. The study was published in the Journal of Drugs in Dermatology.