All news from Pharmacology and Therapeutics
A study led by a team of Massachusetts General Hospital (MGH) investigators has analyzed, for the first time, the mechanisms underlying the use of focused ultrasound to improve the delivery of anti-cancer drugs across the blood-brain barrier into brain tumors.
For exercise, many people cycle to and from work or visit the gym to lift weights. Regardless of the form of training they choose, people exercise to improve their health. But researchers actually know surprisingly little about exactly how different forms of training affect health.
Immunologists at Friedrich-Alexander-Universität Erlangen-Nürnberg have demonstrated that ILC2, a group of rare lymphoid cells, plays a key role in the development of inflammatory arthritis. ILCs have several functional similarities to T-cells and are important agents of the congenital immune system.
Babies who show lower levels of brain activity in response to social stimuli such as peek-a-boo are more likely to be diagnosed with autism spectrum disorder (ASD), according to research involving UCL.
Cell differentiation is a widely studied phenomenon forming the basis of all developmental processes including fetal growth and bone fracture healing. A series of recent studies indicate the emerging role of chondrocyte-to-osteoblast transdifferentiation during bone tissue formation, known as endochondral ossification (replacing cartilage with bone).
Scientists at Scripps Research have developed a urine diagnostic to detect the parasitic worms that cause river blindness, also called onchocerciasis, a tropical disease that afflicts 18 to 120 million people worldwide
Prophylactic administration of tranexamic acid does not reduce postpartum hemorrhage among women with vaginal delivery receiving prophylactic oxytocin, according to a study published in the Aug. 23 issue of the New England Journal of Medicine
Oncogenic osteomalacia is an endocrine disorder induced by small benign tumors (TIO) producing excessive fibroblast growth factor-23 (FGF23). The only way of curing oncogenic osteomalacia is surgical resection of the culprit TIO, which is extremely difficult to detect using conventional imaging modalities due to its small size and variable location in the body
As Liqun Luo was writing his introductory textbook on neuroscience in 2012, he found himself in a quandary. He needed to include a section about a vital system in the brain controlled by the chemical messenger serotonin, which has been implicated in everything from mood to movement regulation. But the research was still far from clear on what effect serotonin has on the mammalian brain
Acute kidney injury (AKI)—sudden and rapid failure of the kidneys—affects up to 20% of hospitalized patients, and up to 70% of ICU patients, according to the new study
Compared with non-drinkers, men who consumed at least seven drinks per week during adolescence (ages 15-19) had three times the odds of being diagnosed with clinically significant prostate cancer
Concomitant exposure to pregabalin and opioids is associated with increased odds of opioid-related death, according to a research letter published online Aug. 21 in the Annals of Internal Medicine