All news from General Medicine

Safety Of Discharging Patients From ICU

According to a study, researchers examined that the safety of discharging adult patients recovering from a critical illness directly home from the intensive care unit (ICU) is unknown. Direct discharge home from the ICU does not increase health care utilization or mortality. The study was published in JAMA Internal Medicine.

Drug Improving Liver Cancer Therapy

Researchers from many international institutions have teamed up to design a more effective drug for liver cancer therapy. Their compound may help improve survival rates and reduce adverse effects. Hepatocellular carcinoma, or primary liver cancer, tend to grow and expand at a fast rate.

If it is not caught early, this means that people who have been diagnosed with it may not survive longer than 11 months. Recent studies show that in the United States, hepatocellular carcinoma is the ninth leading cause of cancer-related deaths. The study was published in the journal PNAS.

Major Trauma Patients And Their Outcomes In The NHS

The NHS in England has saved an additional 1,600 patients with severe injuries since major trauma centers were established in 2012. New findings show the creation of major traumas centers has led to the survival of more than 1,600 patients who have suffered some of the most severe and complicated injuries thanks to top teams of surgeons, doctors, and clinical staff. Patients also spent fewer days in the hospital and had improved quality of life after receiving critical care.

The independent report, which features in the latest issue of Eclinical medicine published by The Lancet, has been compiled by the Trauma Audit and Research Network (TARN) based at The University of Manchester supported by experts at the Universities of Leicester and Sheffield.

Association Between Physical Therapy And ED Revisits for Older Adults

Falls are the leading cause of illness and death among Americans aged 65 and older. In 2014, some 2.8 million older adults visited the emergency department (ED) for a fall-related injury. And over time, the ED visit rate for falls among older adults has grown to 68.8 per 1,000 older adults (as of 2010).

Older adults who visit the ED for a fall are at high risk for both revisiting the ED and dying. In fact, some estimates show that 25 percent of older adults visiting the ED for a fall returned for at least one additional fall-related visit. Fifteen percent of those older adults died within the following year.

Resignation Syndrome Affecting Refugee Children

The researcher examined the raising concerns about an outbreak of a severe trauma-related mental disorder known as traumatic withdrawal syndrome, or resignation syndrome. The recent legal action resulted in the urgent medical evacuation of a child in an unconscious state following a progressive social withdrawal and failure to speak, eat or drink. The child was unresponsive, dehydrated and at risk of death from the physical complications of this extreme state.

Systemic Thyroid Hormone Status During Levothyroxine Therapy In Hypothyroidism

A study of overt hypothyroidism in which participants were treated with levothyroxine to normalize serum TSH levels and measured other objective markers of thyroid hormone signaling. The standard of care for overt hypothyroidism is levothyroxine at doses that normalize serum TSH levels. Whether this approach universally restores thyroid hormone signaling is unknown. The study was published in The Journal of Clinical Endocrinology & Metabolism.

Cutoff Point Defines Non-beneficial Treatment For Older Patients

Researchers reviewed the medical records of 733 admitted patients who received calls for medical emergency teams during hospitalization. The median age was 68 years but a third of the patients were older than 80 years.

Aggressive Life-saving Treatments

UNSW medical researchers are calling for restraint on the use of aggressive life-saving treatments for frail elderly patients at the end of their lives, saying the focus should instead be placed on making patients' last days comfortable and dignified. The study was published in the Joint Commission Journal on Quality and Patient Safety.


Hearing Sound Varies In Different Age Groups

By exploring differences in the way younger and older adults respond to sounds, Western neuroscientists have found that our brains become more sensitive to sounds as we age, likely leading to hearing challenges over a lifetime.

BrainsCAN Postdoctoral Scholar Björn Herrmann and Ingrid Johnsrude, Western Research Chair in Cognitive Neuroscience, examined the auditory cortex responses of participants in their 20s and 60s. What they found was differences in responses to soft and loud sounds. The study was published in the Journal of Neuroscience.

Treating Children With Severe Atopic Dermatitis

Researchers showed that treating children with severe atopic dermatitis remains a challenge because there are so few effective and approved therapies. But there is hope that pipeline therapies, including Janus kinase (JAK) inhibitors and a monoclonal antibody against the IL-31 receptor for the treatment of itch, may address some needs among severely impacted children.

The study was published in the Current Allergy and Asthma Reports.  The researchers reviewed what is known about severe atopic dermatitis in children and identified gaps in treatment and knowledge.