Inside cells, where DNA is packed tightly in the nucleus and rigid proteins keep intricate transport systems on track, some molecules have a simpler way of establishing order. They can self-organize, find one another in crowded spaces, and quickly coalesce into droplets—like oil in water
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Scientists have discovered a 'molecular signature' for the allostatic load – or 'wear and tear' of kidneys – which could help clinicians understand why some kidney transplants don't work as well as expected
Researchers examined a molecular matrix, a hydrogel, to deliver muscle stem cells called muscle satellite cells (MuSCs) directly to injured muscle tissue in patients whose muscles don't regenerate well. In lab experiments on mice, the hydrogel successfully delivered MuSCs to injured, aged muscle tissue and boosted the healing process while protecting the stem cells from harsh immune reactions.
A car accident leaves an aging patient with severe muscle injuries that won't heal. Treatment with muscle stem cells from a donor might restore damaged tissue, but doctors are unable to deliver them effectively. A new method may help change this. The study was published in the journal Science Advances.
In the present retrospective study, scientists explained that higher PIRADS scores are associated with a higher likelihood of the diagnosis of prostate cancer
The coupling of an enzyme with a light-activated catalyst offers great potential for organic synthesis. Catalysts working in pairs can promote more-effective reactions than can the same catalysts used sequentially. The study was published in the journal Nature.
The development of catalytic reactions is a dominant theme in chemistry, especially in industry, where major efforts are underway to develop large-scale chemical processes that are sustainable and avoid producing unnecessary waste. Chemical reactions can be accelerated using many types of catalyst, including metals (or their salts or complexes), small organic molecules, enzymes and light-activated catalysts.
Chronic, frequent tobacco smokers have a decreased number of cannabinoid CB1 receptors, the "pot receptor," when compared with non-smokers, reports a study in Biological Psychiatry
Researchers showed that the battle against disease as it uses visualization as an enabler for scientific discovery. The molecular details it reveals are so precise, it allows the mapping of the entire surface of biological molecules such as proteins and DNA.
Considered as the most advanced and powerful microscope of Australia because of its capability to visualize down to the level of individual atoms, the Titan Krios will begin its working life as part of a suite of transformative technology.
The University of Wollongong’s (UOW) three-meter tall, one-tonne FEI Thermo Fisher Titan Krios cryo-electron microscope allows scientists to see the inner workings of human cells with unprecedented clarity.
A study examined the impacts of dexmedetomidine supplemented intravenous analgesia on morphine consumption and subjective sleep quality in elderly patients after open abdominal surgery. Dexmedetomidine in combination with opioids has been used for postoperative analgesia.
Hospice and palliative care patients who listen to live music in their rooms as part of their treatment feel better both emotionally and physically, and request fewer opioid-based medications, a new study found. Doctors working with seriously ill patients offered them the option to have a flutist play music in their rooms as part of their palliative care, which focuses on improving quality of life and relieving symptoms for patients with serious illnesses.
Certain oral contraceptives may increase the risk of drug-induced Torsade de Pointes in women with preexisting risk factors, according to the new study
According to a study, researchers determined that a growing partnership between the Military Health System and permanent civilian trauma institutions is being fostered. The study was published in the Journal of the American College of Surgeons.