Mutations in a gene involved in steroid signaling likely contribute to preterm birth, report Johanna Huusko of the University of Oulu and Cincinnati Children's Hospital Medical Center and colleagues, in a study of European women who had experienced at least one early delivery
Use of the novel radiopharmaceutical radium-223 dichloride (Xofigo, Bayer) in prostate cancer should be restricted, according to the European Medicines Agency's Pharmacovigilance Risk Assessment Committee (PRAC)
Systemic lupus erythematosus (SLE) is a chronic disease that causes inflammation and tissue damage. SLE can involve many organs and systems and has a poor prognosis. It is one of a large group of autoimmune disorders, which occur when the immune system attacks the body's own tissues and organs
Stanford researchers discovered that a receptor that binds to nicotine and to clusters of beta-amyloid molecules is found on certain types of immune cells that can act as suppressors and regulators of the immune system
Only about one-third of young children in the U.S. receive recommended screenings or surveillance designed to catch developmental delays. Findings reveal wide variations in rates across states, with as few as 17% of children under three years old receiving developmental screening in the lowest performing state
Matt Costa, Professor of Orthopaedic Trauma at the University of Oxford and President-elect of the Fragility Fracture Network (FFN), explains the need for global action to provide better care for people suffering from hip fractures and other fractures that result from increased fragility
A new study has shown that people who regularly eat oranges are less likely to develop macular degeneration (MD) than people who do not eat oranges
A team of bioengineers at UC San Diego has answered a question that has long puzzled neuroscientists, and may hold a key to better understanding the complexities of neurological disorders: Why are axons, the spindly arms extending from neurons that transmit information from neuron to neuron in the brain, designed the way they are?
Trauma is the sixth leading cause of death worldwide, and recent studies suggest that 16% of renal (kidney) trauma occurs from a penetrating injury, such as a gunshot wound, stabbing or piercing injury from a car accident
The US Food and Drug Administration (FDA) has approved enzalutamide (Xtandi, Astellas/Pfizer) for the treatment of men with castration-resistant prostate cancer (CRPC), according to a joint company press statement. The approval extends the indication for the oral therapy, which was previously approved for men with metastatic CRPC
A team of researchers has uncovered a specific gene variant associated with an adverse drug reaction resulting in liver injury in a people with multiple sclerosis (MS). It is the first time researchers have been able to establish a validated genetic marker for a drug-induced harm in people with MS
A revolutionary gene editing technique hailed as the future of disease eradication and mooted for a Nobel prize may be less precise and cause more cell damage than previously thought, said researchers