Researchers at the Kennedy Institute and Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, working with clinicians at NHS Lothian, have found that injection of the anti-TNF drug adalimumab into Dupuytren's disease nodules results in the reduction of the cell characteristics responsible for the progression of Dupuytren's disease
New research uncovers how a sticky protein called fibronectin which promotes the activity of estrogen in breast cancer cells. The study, "Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells," which will be published July 6 in the Journal of Cell
A new study finds that severe childhood trauma and stresses early in parents' lives are linked to higher rates of behavioral health problems in their own children
Knee pain in active patients over 40 is often difficult to treat but according to researchers presenting their work today at the American Orthopaedic Society for Sports Medicine's (AOSSM) Annual Meeting in San Diego utilizing a special kind of allograft may be a step in the right direction
Patients who undergo combined cataract surgery, or removal of cataracts combined with treatment of other eye disorders during the same procedure, have the higher incidence of acute postoperative endophthalmitis (acute POE) compared with those who have cataract surgery alone, results of a French nationwide database show
Women in New Zealand who experienced severe maternal morbidity (SMM) often do not receive information, an offer of support, or a follow-up appointment before their hospital discharge, according to a study published in the June issue of the International Journal of Gynecology & Obstetrics
New nuclear medicine tracers could help medical researchers find a cure for Alzheimer's and other neurodegenerative diseases. The research was presented today at the SNMMI 2018 Annual Meeting, June 23-26 in Philadelphia
A team of researchers from China and Singapore has discovered a region in the brain that appears to play a central role in regulating eating behavior. In their paper published in the journal Science, the group describes their study of the brain region and what they found. Sabrina Diano with the Yale University School of Medicine offers a Perspective piece on the work done by the team in the same journal issue
A significant portion of kidneys from deceased donors are discarded because they literally don't make the grade—a scoring system known as the kidney donor profile index (KDPI) that aims to predict how long a donor kidney will last in an intended recipient based on a variety of factors, including the donor's age, size and health history
First-trimester screening of pregnant women for asymptomatic bacteriuria—higher than normal bacteria levels without symptoms of a bladder infection—is recommended by the Canadian Task Force on Preventive Health Care in an updated guideline in CMAJ
An analysis of large randomized controlled trials, however, reveals that extended use of tamoxifen is linked with a two-fold increased risk of developing endometrial (womb) cancer, when compared with standard 5 years of tamoxifen
A Finnish study published in the respected SLEEP journal shows that a variation in the melatonin receptor 1A (MTNR1A) gene is linked to the risk of Alzheimer's disease in the elderly. The same research team has previously demonstrated that the same genetic variation reduces tolerance to shift work among the working age population