All news from Anaesthesiology

Atomic Structure Of Tropoelastin

A study shows that the stretchiness that allows living tissues to expand, contract, stretch, and bend throughout a lifetime is the result of a protein molecule called tropoelastin. Remarkably, this molecule can be stretched to eight times its length and always returns back to its original size.

Researchers have decoded the molecular structure of this complex molecule, as well as the details of what can go wrong with its structure in various genetically driven diseases. Tropoelastin is the precursor molecule of elastin, which along with structures called microfibrils is the key to the flexibility of tissues including skin, lungs, and blood vessels.

Nanoparticles Use To Fry And Eradicate Cancer Cells

A new study showed that researchers developing nanoparticles that can zap tumors with significant amounts of heat under a low magnetic field. That's the promise of heated magnetic nanoparticles, a futuristic-sounding technology that could one day be used to fry and eradicate cancer cells without harming healthy tissue elsewhere in the body. The study was published online in the journal Small.

Association Between Sedation and General Anesthesia

Sedation, together with analgesia, amnesia and muscle paralysis, is the end result of general anesthesia, which is an induced, reversible and controlled loss of consciousness. Sedation, on its own, is the depression of awareness, whereby a patient response to external stimuli becomes limited. Sedation may be minimal, moderate or deep.

Doctors Can Improve The Quality Of Life For Serous Ill Patients

The research examined that palliative care can sharply reduce medical costs, Doctors can improve the quality of life for their seriously ill patients while also reducing the patients' medical expenses if they make use of one particular care model.

The biggest hurdle might well be the words used to describe it, said Dr. Jeanine Ellinwood, who leads a team in the specialized field. People hear them, she said, and think immediately of hospice care. 

Risk For Infective Endocarditis After Diagnosis

The risk for infective endocarditis climbs significantly after many invasive therapeutic and diagnostic procedures and is especially high after some common ones, such as bronchoscopy and coronary angiography, conclude investigators of a large observational study that included cases from 1998 to 2011.

The analysis, which excluded dental procedures in Sweden, invites at least a partial reappraisal of guidelines from a decade ago that dramatically cut reliance on antibiotic prophylaxis with dental and many nondental invasive procedures. The study was published in the Journal of the American College of Cardiology.

New Insights Of Human Anatomy, Joints

A joint is defined as a point where 2 bones articulate or make contact. Joints can be classified in 2go ways:

(1) histologically, based on the type of connective tissue which is dominant in the joint 

(2) functionally, based on the amount of movement permitted between the bones forming the joint. Based on the histological classification, the 3 types of joints in the human body are fibrous, cartilaginous, and synovial.

Astronauts Feel Painful In Spaceflight

Headaches and eye problems are common among visitors to the International Space Station. Astronaut Chris Hadfield remembers the headaches in his five months of spaceflight on the International Space Station in 2012 and 2013. It was a constant pain in his sinuses, along with stuffiness. The Canadian astronaut blew his nose frequently to clear his head and used mild pain medication to help him keep up with his demanding spaceflight schedule.

Exosomes In The Inner Ear Used As Biomarker

Researchers show the presence of exosomes in the inner ear and to characterize the changes in their protein content in response to ototoxic medications. Exosomes are nanovesicles involved in intercellular communications. They are released by a variety of cell types; however, their presence in the inner ear has not been described in the literature.

The study is to determine if exosomes are present in the inner ear and, if present, characterize the changes in their protein content in response to ototoxic stress. In this laboratory investigation, inner ear explants of 5-day-old Wistar rats were cultured and treated with either cisplatin or gentamicin. Hair cell damage was assessed by confocal microscopy. Exosomes were isolated using ExoQuick, serial centrifugation, and mini-column methods.