All news from Anaesthesiology

Elucidation Of Molecular Mechanism Of The GPCR-Arrestin Complex

According to new study, researchers examined the molecular mechanism of activation of the GPCR-arrestin complex. The effectiveness of new drugs depends crucially on a fundamental understanding of the complex processes within the cells of the body. They have deciphered an important molecular step of cellular signal transmission. Their findings could help the development of specific drugs against various diseases, such as asthma and high blood pressure. The study was published in the journal Nature.

Liposomal Bupivacaine Reduce Inpatient Opioid Prescription

According to a new study, researchers showed that Liposomal bupivacaine use in patients undergoing total knee arthroplasty is not associated with clinically meaningful reductions in inpatient opioid use, resource utilization, or opioid-related complications. The study was published online in Anesthesiology. Although some trials suggest benefits of liposomal bupivacaine, data on real-world use and effectiveness is lacking.

Dying Cells Have Cellular 'Death Code'

Researchers believe that the molecular "code" that unleashes this more violent variety of cell death. Dying cells generally have two options: go quietly, or go out with a bang. The latter, while more conspicuous, is also mechanistically more mysterious. The study was published in Molecular Cell.

Microbes In Aircrafts Much Like That Of Offices And Homes

According to a new study, researchers found that the community of bacteria found in homes, offices and aircraft cabins. Believed to be the first to comprehensively assess the microbiome of aircraft, the study found that the bacterial communities accompanying airline passengers at 30,000 feet have much in common with the bacterial communities surrounding people in their homes and offices.

Enzyme Telomerase Plays A Major Role In Aging

A study determine that Cancer, aging-related diseases and other illnesses are closely tied to an important enzyme called "telomerase." Researchers reports that the deepest scientific understanding yet of this once-mysterious enzyme, whose catalytic core where most of its activity occurs can now be seen in near atomic resolution. The study was published in the journal Cell.

Patients At Risk Readmission To Emergency Rooms

According to a study, researchers determined that hospital patients have been at a high risk for adverse effects after they are discharged. These effects can be defined as unplanned bad circumstances that are directly related to the patient's diagnosis, clinical conditions or the care they received while in the hospital. Many times these events lead to the patient being readmitted, going to the emergency room or, even worse, dying.