All news from Anaesthesiology

Magnetic Resonance Spectroscopy Reveals Effects Of Targeted treatments

Researchers investigated the mechanisms behind a potential targeted treatment for a subtype of the deadly brains tumors called gliomas. They describe using magnetic resonance spectroscopy (MRS) imaging which reflects metabolic rather than structural aspects of tissues to determine whether treatment with an investigational IDH1 inhibitor reduced levels of a tumor-associated metabolite in patients with IDH1-mutated gliomas participating in a clinical trial. The study was published in Nature Communications.

To Compare Spinal-Epidural With Epidural Analgesia And Their Effects

A study is to determine combined spinal-epidural with epidural analgesia in terms of their effect on duration of stage I labor, maternal, and neonatal outcomes. Neuraxial anesthesia is considered as the gold standard in the control labor of pain. Its variants are epidural analgesia and combined spinal–epidural analgesia. Few studies, as yet, have investigated the duration of labor as a primary outcome. Some authors have suggested that combined spinal-epidural analgesia may reduce labor duration but at the moment the benefit of shortening labor is uncertain.

Thyroid Gland Carry A Greater Risk For Malignancy

New research examined that nodules located in the upper pole of the thyroid gland may carry a greater risk for malignancy than those in the lower pole. Sonographic characteristics of nodules such as microcalcifications, hypoechoicity, infiltrative margins, increased vascularity, and taller-than-wide are all known to be associated with greater malignancy risk, but no prior study has examined the risk about a location in the upper versus lower pole of the thyroid.

Incubation Period Is A Key In Spread Of Disease

The distribution of incubation times in most cases, they contend, is close to 'lognormal' meaning that the logarithms of the incubation periods, rather than the incubation periods themselves, are normally distributed. Working with a simple mathematical model in which chance plays a key role, researchers calculated how long it would take a bacterial infection or cancer cell to take over a network of healthy cells.