A new method enables genes in living T-cells in mice to be modified quickly and efficiently. The method utilized plasmids, a tried-and-tested method of genetic engineering. Researchers from the University of Basel reported in the Journal of Immunology.
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Researchers have revealed evidence that shows a more complex and elaborate role for the body's hard-working G protein-coupled receptors (GPCRs) than previously thought, suggesting a conceptual advance in the fields of biochemistry and pharmacology.
Researchers team have revealed for the first time uncovered the molecular details of protein crystal nucleation, a process with great medical and scientific relevance. The team also developed a new methodology to study a broad class of systems that have remained elusive to date. The study was published in Nature.
A study investigates the application of nerve stimulator-guided thoracic paravertebral nerve block (TPVB) plus general anesthesia(GA) in small-incision lung cancer surgery. Treatment for lung cancer depends on tumor histology, tumor extent, and other patient-specific factors; however, surgery remains the cornerstone in treating this disease, and it offers the only chance for long-term survival.
Research used neuroimaging techniques to analyze the brains of more than 3,800 volunteers in different countries. The largest study of its kind ever conducted set out to investigate anatomical similarities and differences in the brains of individuals with different types of epilepsy and to seek markers that could help with prognosis and treatment. The study was published in the journal Brain.
In the study, researchers conducted a large randomized phase 3 trial to explain combination immunotherapy could be a new standard of care for some patients with advanced renal cell carcinoma (RCC)
Present study explains that Osteoclast secretion SLIT3 plays an osteoprotective role by synchronously stimulating bone formation and inhibiting bone resorption, making it a potential therapeutic target for metabolic bone diseases
The main objective of the study is to characterize toxicities observed with palbociclib resulting in dose modifications and prescriber preferences in modifying palbociclib dosage in response to treatment-related toxicities outside the context of a clinical trial
According to French researchers, intravitreal anti-vascular endothelial growth factor (anti-VEGF) medications in general do not appear to increase the risk of extraocular hemorrhagic or other adverse events, though questions remain
In the study, researchers said that women with inflammatory bowel disease (IBD) should be given more advice about pregnancy so they can make informed choices about whether to have a family or not