All news from Anaesthesiology

Unstructured Proteins: Ultra-High-Affinity Interactions Seen

Researchers have discovered a previously unknown way in which proteins interact with one another and cells organize themselves. This new mechanism involves two fully unstructured proteins forming an ultra-high-affinity complex due to their opposite net charge. Proteins usually bind one another as a result of perfectly matching shapes in their three-dimensional structures.

Effectiveness of HIV testing in Emergency Departments

South Africa has the worst epidemic of HIV in the world. According to the Joint United Nations Programme on HIV/AIDS, 19% of the global number of people living with HIV are in South Africa. Many people in South Africa and around the globe do not even know they have HIV.

Enzymes To Trigger Onset Of Kidney Disease

A new study including the onset of kidney disease in a major marker for kidney disease development. Scientists have discovered nano-sized 'shuttles,' which transport a damaging enzyme outside of the kidney cells for it to begin the scarring process on the surface. The study is hoped that it could lead to new therapies to try to block the tiny microvesicles about 100 nanometers in diameter and potentially stop the disease in its tracks. The study was published in the Journal of the American Society of Nephrology.