Many of the most fundamental questions about the nature of life are illuminated at the scale of a single biological molecule. Studies of single-molecule biophysics combine in vivo(in live cells) and in vitro investigations.
People with Alzheimer’s have a higher production rate of tau proteins than healthy individuals, according to a study published in Neuron. Researchers found that tau production and secretion from nerve cells appears to be an active process in the natural course of Alzheimer's disease.
Multimodal pain management is associated with fewer perioperative complications, less opioid use and shorter hospital stays, according to a database study of more than 1.5 million joint replacements.
In a study conducted at The University of Texas at Dallas, researchers have demonstrated a method to accelerate motor skill recovery after a stroke by helping the brain reorganize itself more quickly.
Researchers have discovered a previously unknown way in which proteins interact with one another and cells organize themselves. This new mechanism involves two fully unstructured proteins forming an ultra-high-affinity complex due to their opposite net charge. Proteins usually bind one another as a result of perfectly matching shapes in their three-dimensional structures.
A team of UCLA researchers found that a metabolite therapy was effective in mice for treating a serious infection of the colon known as Clostridium difficile infection, or C. difficile.
An audiologist from the UK’s leading tinnitus clinic is urging sufferers to seek support after a study has revealed considerable regional variation in tinnitus service provision across the UK, particularly in the availability of psychological treatments.
Study finds that early dermatology consultation for presumptive cellulitis can improve patient outcomes, reduce costs and reduce unnecessary hospitalization.
South Africa has the worst epidemic of HIV in the world. According to the Joint United Nations Programme on HIV/AIDS, 19% of the global number of people living with HIV are in South Africa. Many people in South Africa and around the globe do not even know they have HIV.
When it comes to battling obesity, physicians may not be offering patients the best chances for success.
Four new polyhydroxy steroidal glycosides; culcinosides A–D (1, 2, 4, and 7), along with three known compounds; echinasteroside C (3), linckoside F (5), and linckoside L3 (6) were isolated from the ethanol extract of starfish Culcita novaeguineae.
A new study including the onset of kidney disease in a major marker for kidney disease development. Scientists have discovered nano-sized 'shuttles,' which transport a damaging enzyme outside of the kidney cells for it to begin the scarring process on the surface. The study is hoped that it could lead to new therapies to try to block the tiny microvesicles about 100 nanometers in diameter and potentially stop the disease in its tracks. The study was published in the Journal of the American Society of Nephrology.