No advantages, clinical or otherwise, were seen from liberal use of red blood cell (RBC) transfusions to keep hemoglobin levels up in patients undergoing on-pump cardiac surgery, in a randomized noninferiority trial with more than 4800 patients. The study is published in the American Heart Association (AHA) 2017 Scientific Sessions.
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A new study published in New England Journal of Medicine suggest that quadrupling the dose of inhaled steroids temporarily when asthma control begins to deteriorate could reduce the risk of a severe asthma attack.
Kidasha, an organization working for the better future of severely disadvantaged children living in crisis and chronic poverty in Nepal, has called for concerted efforts to provide better protection and development opportunities for Nepali children at risk especially in the rapidly growing, sprawling urban centers.
According to findings from the Spanish Sleep Network, noninvasive ventilation (NIV) improves cardiac structure and function to a greater extent than CPAP in patients with obesity hypoventilation syndrome (OHS).
In a step toward better diagnosis and treatment of digestive conditions, such as inflammatory bowel disease, scientists report in ACS Biomaterials & Engineering that they have developed a first-of-its-kind collagen-based membrane for use in microchips.
The membrane is more natural than others that are available, and it could allow organs-on-chips to more accurately replicate how healthy intestinal cells become diseased and how they react to drug treatments.
Patients with schizophrenia are considered to have many risk factors for the development of cancer. But the incidence of breast cancer in women with schizophrenia compared with the general population remains uncertain. A new study, published in JAMA Psychiatry, evaluate the link between schizophrenia and the risk of breast cancer, and found that incidence of breast cancer is higher among women with schizophrenia than the incidence among the general female population.
University of Glasgow are leading new tests into the viability of using an innovative, new microwave system to treat human papillomavirus (HPV).
Metabolic changes in cells can occur at the earliest stages of the disease. In most cases, knowledge of those signals is limited, since we usually detect disease only after it has done significant damage.
Researchers have opened a window into the cell by developing an optical tool that can read metabolism at subcellular resolution, without having to perturb cells with contrast agents or destroy them to conduct assays. As reported in Science Advances, the researchers were able to use the method to identify specific metabolic signatures that could arise in diabetes, cancer, cardiovascular and neurodegenerative diseases.
The millions of cellular machines called ribosomes, which translate the genetic code carried by DNA into proteins, have long been thought to all be identical. A new study published in the journal Science Advances suggests that genetic variation in ribosomal RNA, the most essential component of the ribosome, may influence how much and which proteins are made. This finding could explain why ribosomal genes have been linked to developmental disorders.
Researchers at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) identified thirdhand smoke, the toxic residues that linger on indoor surfaces and in dust long after a cigarette has been extinguished, as a health hazard nearly 10 years ago. Now a new study has found that it also increases lung cancer risk in mice.
Researchers have shown an innovative antibody delivery method could be an effective way to prevent and treat Ebola infection. They demonstrated that delivering a monoclonal antibody gene to a cell through a viral vector — a process that bypasses the need for the host to generate a natural immune response — provided up to 100% protection against infection in mice. The mice expressed the antibody for more than 300 days.Their findings were published in the Journal of Infectious Diseases.