Researchers from Universities of Cambridge and Copenhagen have developed a new method to predict the physical stability of drug candidates, which could help with the development of new and more effective medicines for patients.
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Accessory ossicles of the foot and ankle are normal variants of bone development that usually remain asymptomatic. However, they may be involved in various disorders and become a source of pain such as in fractures, dislocations, degenerative changes, osteonecrosis, osteoarthritis, osteochondral lesions, avascular necrosis, and irritation or impingement of adjacent soft tissues.
In the Urological Society of Australia and New Zealand's annual scientific meeting, Robert Nam, chair of urologic oncology at the Sunnybrook Health Services Centre, raised the question whether radiation oncologists were over-treating low-risk prostate cancer or whether under-educated patients were demanding over-treatment.
In a study published in the Journal of Clinical Investigation, the researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have identified genetic clues that explain how breast cancer spreads, or metastasizes — findings that may lead to better treatments or approaches to prevent its spread at the onset.
A study observed the new insights about how E. coli bacteria mutate in response to a life-threatening challenge. Bacteria are stealthy organisms. They can multiply in minutes and evolve to survive what we throw at them including antibiotics. The study was published in Proceedings of the National Academy of Sciences (PNAS).
According to a new clinical study conducted by scientists at British American Tobacco, it has been revealed that when smokers switch completely from cigarettes to glo, their exposure to certain cigarette smoke toxicants is significantly reduced, in some cases to levels comparable to those seen in smokers who quit smoking completely.
In this study, alkaline-degradable microgels based on poly(N-vinylcaprolactam) (PVCL) were prepared and analysed with their regard to stabilise retinol which acts as a model vitamin (vitamin A1). Biocompatible materials that can encapsulate large amounts of nutrients while protecting them from degrading environmental influences are highly desired for extended manned spaceflight.
The study reveals that children born to women who take a commonly used diabetes medication metformin during pregnancy may have an increased risk of being overweight or obese
All pregnant women are being urged to be screened for syphilis, as cases of neonatal syphilis have increased in the United States in recent years, according to an advisory from the University of Hawaii School of Medicine.
An international team has successfully tested a molecule inhibitor of interleukin-18, a protein involved in immune response. These encouraging results in terms of safety and efficacy are paving the way for a new kind of treatment for serious inflammatory diseases such as Still's disease. The study was published in the journal Annals of the Rheumatic Diseases.
Infants who have higher amounts of the bacterium Lactobacillus present in their nose or upper part of the throat during an acute respiratory syncytial virus (RSV) infection are less likely to develop childhood wheezing later in life, according to a study published in the Journal of Allergy and Clinical Immunology.