A new study led by Australian researchers looked at the effects of aerobic exercise on a region of the brain called the hippocampus, which is critical for memory and other brain functions. The researchers find that aerobic exercise can improve memory and maintain brain health as we age.
In this study, researchers examined to assess the association between SCD and ATH, and the diagnostic accuracy of the SDCS for ATH in pre-school children with SCD. The Sleep Disturbance Scale for Children (SDSC) is a questionnaire validated for the Portuguese language that has been increasingly used in studies on SDB in children and adolescents. The causes of ATH are not yet fully known, however, recurring chronic or acute inflammation seem to be involved.
Human gut microbiota plays an essential role in both healthy and diseased states of humans. In the past decade, the interactions between microorganisms and tumors have attracted much attention in the efforts understanding various features of the complex microbial communities, as well as the possible mechanisms through which the microbiota are involved in cancer prevention, carcinogenesis, and anti-cancer therapy.
The researchers from the Wayne State University School of Medicine demonstrate how the human brain responds during cold exposure and what brain mechanisms may endow prolonged resistance to cold exposure. The study, published in the journal NeuroImage, hypothesize that by generating a stress-induced analgesic response in gray matter, the person may promote the spontaneous release of opioids and cannabinoids in the brain.
Although obesity has been considered a risk factor for more-severe cases of the flu, a new study, published in the International Journal of Obesity, found that it is not a risk factor for severe acute respiratory illnesses, including the flu, in children or adults.
In this study, researchers examined more often than either of them suspects about whether a medical test or medicine is truly necessary, according to findings from a new poll of Americans over age 50. Improving communication about that mismatch of opinions, the poll suggests, might reduce the use of unneeded scans, screenings, medications and procedures and health care costs as well.
A new study estimated that role of intraoperative intravenous lidocaine infusion has been previously evaluated for pain relief, inflammatory response, and post-operative recovery, particularly in abdominal surgery. The present study is a randomized double-blinded trial in which we evaluated whether IV lidocaine infusion reduces isoflurane requirement, intraoperative remifentanil consumption and time to post-operative recovery in non-laparoscopic renal surgery.
To study the biological functions and structural mechanisms of these histone PTMs, an obligatory step is to prepare a sufficient amount of homogeneously modified histones. In the post-genome era, epigenetics has received increasing attentions in recent years. The post-translational modifications (PTMs) of four core histones play central roles in epigenetic regulation of eukaryotic genome by either directly altering the biophysical properties of nucleosomes or by recruiting other effector proteins.
New research will improve how scientists "see inside" molecular structures in solution, allowing for much more precise ways to image data in various fields, from astronomy to drug discovery. The new method will allow for the visualization of many more biological molecules, providing critical information about what is inside molecules to scientists who currently can only access their outer shape or envelope. This study was published in Nature Methods.
The research was conducted to find that metformin (hazard ratio, 1.02) and statins association with the incidence of ovarian cancer patients diagnosed with type II diabetes (T2D) from the data obtained from the national registry of Finland.
In this study, researchers analyzed the prevalence of GSs among community-dwelling older adults in Moscow, based on the questionnaire and the comprehensive geriatric assessment (CGA). A cross-sectional study was conducted in four community clinics in Moscow. A total of 1,220 patients completed a screening questionnaire, and 356 of them also underwent a comprehensive geriatric assessment (CGA).
Researchers conducted a study, they assemble efforts in clinical and basic research on childhood nephrotic syndrome, focusing on kidney transplant patients. The aim is to identify the genetic mutation profile associated with the disease and thereby facilitate early diagnosis, providing a foundation for more accurate medical decisions and enhancing family counseling. This study was published in the journal Transplantation.