All news from Anaesthesiology

Duchenne Muscular Dystrophy Analysis

Researchers are searching for therapies that might slow the progression of DMD while also investigating genetic and other approaches to disrupt the underlying disease mechanism. Examining data from the large TREAT-NMD Duchenne muscular dystrophy database, investigators were able to confirm that corticosteroid treatment can delay some of the clinical effects of DMD and that there is greater variability among patients in the progression of the disease than reported. These findings appear in the Journal of Neuromuscular Diseases . 

Study Finds, Drug Safety in Hospitalized Pediatric Patients

The results of the study, recently published in BMC Pharmacology and Toxicology, identified 19 ADRs out of a total of 1,083 hospital admissions.The most frequently prescribed drug classes were antibiotics and anti-inflammatory drugs. The approximate incidence of ADRs in children was17per 1,000 children.Most of the ADRs involved antibiotics and 21% of the ADR’s were categorized as “preventable”. The severest ADRs observed during the study were haemolysis and toxic epidermal necrolysis.

Assessment of Patient and Physician Ratings of Surgical Scars.

A new study published in the JAMA Facial Plastic Surgery has showed that disagreement between physician- and patient-reported scar assessment is not uncommon. Neither patients nor clinicians consistently detect differences in scars using current scar assessment instruments. Patients and physicians differ in their evaluation of surgical scars. Scar instruments that better integrate both patient and clinician scar ratings may aid in determining the most salient features of cutaneous scars.

Lung recritment assessed by Electrical Impedance Tomography

The aim of the present study was to compare, in intubated patients with acute hypoxemic respiratory failure (AHRF) and acute respiratory distress syndrome (ARDS), lung recruitment measured by P-V curve analysis, with dynamic changes in poorly ventilated units of the dorsal lung (dependent silent spaces [DSSs]) assessed by electrical impedance tomography (EIT). Researchers hypothesized that DSSs might represent a dynamic bedside measure of recruitment.