A new study reported that Streptomyces sp. strain SM8, isolated from Haliclona simulans, possesses antifungal and antibacterial activities and inhibits the calcineurin pathway in yeast.
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The Mayo clinic researchers, who published the study in the January 24 issue of the Arthritis and Rheumatology, analyze the risk of rheumatologic disease flare and adverse effects in patients with preexisting rheumatologic disease receiving modern cancer immunotherapy called immune checkpoint inhibitors.
The aim of this study was to determine the independent effects of operative time and surgical invasiveness on perioperative outcomes afterwards spinal fusions for adult spinal deformity. Adult spinal deformity ( ASD ) is common in the adult population, with previous reports estimating that there are over 500,000 adults with curves over 30 ° in the United States
A new, multicenter study published in JAMA Pediatrics has found that most National Institutes of Health (NIH) grants awarded to researchers in paediatrics during the past five years have been limited to physicians in senior positions at a small number of institutions. The findings indicate an overall downward trend in funding for pediatric research, particularly among early-career physician-scientists.
The study's aim is to estimate the prevalence of High-Risk Human Papillomavirus (HR HPV) infection among Iranian healthy women undergoing routine cervical cancer screening using COBAS HPV typing assay. The results of the current study might help us in making public health decisions regarding the cervical cancer screening and HPV vaccination to prevent and decrease the incidence of this cancer in Iran.
Human papillomavirus (HPV), the culprit behind cervical cancer and some forms of head and neck cancer may hide in small pockets on the surface of tonsils in people not known to carry the virus. The finding, reported in the Journal of the American Medical Association, could be pivotal for the prevention of oropharyngeal cancers that form on the tonsils and tongue.
A new type of membrane test strip for the quantitative immunochromatographic rapid-test has been developed that will be able to accurately and quickly make an early diagnosis of an acute myocardial infarction through the presence of disease markers in blood, as well as to identify various things such as sepsis, a pregnancy's duration, and viral & bacterial infections.
The researchers noted that New Zealanders are particularly appropriate to study regarding this issue because high exposure to lead has been observed among children of all levels of family income. That would help eliminate economic class as a mitigating factor. The findings were published in JAMA Pediatrics.
Renal cell carcinoma (RCC) frequently metastasizes to the lungs, lymph nodes, bones, and liver. Although RCCs have been shown to metastasize to virtually all organs, both rectal and vaginal metastases are exceptional. This is the fifth reported case of RCC metastasis to the rectum and the first one in a patient without a prior diagnosis of RCC.
Houston Methodist researchers have a new explanation for what causes the lungs' airways to close during asthma attacks. The discovery published in the Journal of Experimental Medicine holds promise for developing a new class of drugs different from the steroids currently used to treat asthma.
Northwestern Medicine scientists and international collaborators discovered mutations that cause improper drainage and a buildup of ocular pressure leading to one form of congenital glaucoma, and identified a path towards future treatments for the disease.
Researchers report, amyloid positivity, according to positron emission tomography (PET) findings, differs among the main clinical variants of primary progressive aphasia (PPA). The findings were published in the JAMA Neurology.