A modified version of iPS methodology, called interrupted reprogramming, allows for a highly controlled, potentially safer, and more cost-effective strategy for generating progenitor-like cells from adult cells. As demonstrated in the journal Stem Cell Reports, the adult mouse respiratory tract cells called Club cells into large, pure populations of induced progenitor-like (iPL) cells, which retained a residual memory of their parental cell lineage and therefore generated mature Club cells. These cells showed potential as a cell replacement therapy in mice with cystic fibrosis.
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A new study has found that the men who were tried for their role in the Rwandan genocide appealing that they are actually very good people. That is the most common way accused men try to account for their actions in testimony before the International Criminal Tribunal for Rwanda. The results appear in the journal Social Problems.
According to results of a UMass Lowell-Washington Post poll released, a majority of Americans believe that it is not safe for children to play tackle football before they reach high school,
A research at Oregon State University showed that a type of soil-dwelling bacterium produces molecules that induces death in melanoma cells . The molecule is a secondary metabolite, also known as a natural product, of Streptomyces bottropensis . The study findings were published in the Journal of Biological Chemistry .
It's the conversation no one wants to have, but talking to patients and their families about death is inevitable for healthcare professionals. To address the limited clinical opportunities nursing students have to experience palliative care and end-of-life conversations, the University of Houston College of Nursing is now using a high-fidelity mannequin to simulate these challenging interactions.
The cancer death rate dropped 1.7% from 2014 to 2015, continuing a drop that began in 1991 and has reached 26%, resulting in nearly 2.4 million fewer cancer deaths during that time. The data is reported in Cancer Statistics 2018, the American Cancer Society's comprehensive annual report on cancer incidence, mortality, and survival. It is published in CA: A Cancer Journal for Clinicians and is accompanied by its consumer version: Cancer Facts and Figures 2018.
A combination of two antibiotics is often prescribed to treat community-acquired pneumonia in children but a JAMA Pediatrics study is now showing that amoxicillin alone, rather than combined with azithromycin, is just as effective and a better choice as it relates to efforts to curb antibiotic resistance.
Artificial polyelectrolytes can mimic the interactions of biological macromolecules such as nucleic acids, proteins, and polysaccharide-protein conjugates. Such synthetic polyionic complexes are expected to serve as novel platforms to stabilize and deliver drugs, proteins, or nucleic acids. In the journal Angewandte Chemie, Chinese investigators have introduced a versatile, commercially applicable preparation strategy of such nanomaterials with tunable morphology. The preparation of libraries of these low-dimensional bio-relevant nanostructures can be envisaged.
New open?access article published in the 1 issue of the Journal of the American College of Cardiology [JACC] has revealed the feasibility and potential of the PlaqueTec Liquid Biopsy System™ (LBS) to detect biomarkers for coronary artery disease (CAD). The system reported results from the first?in?human studies of the LBS in detecting biomolecular gradients in diseased coronary arteries of symptomatic patients undergoing percutaneous coronary intervention (PCI) procedures.
New research by a team from London's Kingston University has revealed how the bacterium can infiltrate micro-organisms called amoebae , multiplying within its cells while protected from its host from harsh environmental conditions
The sequencing of the human genome has made it possible. The biochemists confirmed the cause of initially unclear symptoms of patients in Israel. Such a disorder is 'MPS III-E', originally also called 'Dierks's disorder' after its discoverer. The researchers are now presenting their analysis in the journal Genetics in Medicine, published by the Nature Publishing Group.
In a new study, researchers have validated the 'Escala de Preocupación por el Cáncer – EPC' (an equivalent of the Cancer Worry Scale) to evaluate the fear of suffering from cancer. The study, published in Medicina Clínica, has revealed that the EPC is a valid and reliable scale for evaluating concern about cancer in healthy people.