The suite of genes early-response cells was defined by factors such as age and previous exposures to viruses, according to a study by the Perelman School of Medicine at the University of Pennsylvania and Children's Hospital of Philadelphia (CHOP). Better understanding how early infections influence long-term immune response has implications for the diagnosis and treatment of young patients who suffer from acute respiratory tract infections.
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In a new study published in the journal Nature Communications , Japanese researchers report a new mechanism for regulating glucose uptake by the liver which has implications for type 2 diabetes and its treatment.
A proposed novel modeling of an oral methylphenidate formulation for attention-deficit/hyperactivity disorder (ADHD) goes beyond the traditional relating of in-vitro dissolution and drug release with in-vivo serum drug levels, to specify the amount and time of drug release which can best evoke clinical benefit. The proposed model-based approach was published in Clinical Pharmacology & Therapeutics.
According to preliminary research presented at the American Stroke Association's International Stroke Conference, a diet, known as the MIND diet, created by researchers might help substantially slow cognitive decline in stroke survivors. The findings are significant because stroke survivors are twice as likely to develop dementia compared to the general population.
A recent study, Race, Preoperative Risk Factors, and Death After Surgery, you have found that black children are more than twice as likely to die following surgery than white children and describe race-specific models to predict surgical outcomes . The study findings will be published online in the February 2018 issue of Pediatrics
In a new study published in JAMA Internal Medicine, the high rate of false-positive results identified in the VHA’s LCS demonstration project has caused concern about whether lung cancer screening (LCS) should be implemented in the population. By re-examining the data, researchers found that the high false-positive rate results in amore concerning harm-to-benefit ratio for those eligible persons at lower LC risk, but a much better harm-to benefit ratio for high-risk patients.
New research findings suggest that higher high-density lipoprotein (HDL) concentrations may be protective against acute kidney injury (AKI) after cardiac surgery. The studies were published in the Journal of the American Heart Association
Acupuncture can be useful for reducing vasomotor symptoms (VMS) in perimenopausal and postmenopausal women, according to results of a systematic review and meta-analysis. The new findings were published in the Journal of Alternative and Complementary Medicine.
Pediatric patients with cancer who have access to specialized pediatric palliative care (SPPC) are less likely to receive high-intensity care at the end of life, according to a study published in the Journal of Clinical Oncology.
New research findings has implications for both wound healing in the eye and for changes in vision like cataracts. The results were recently published in the Nature journal Scientific Reports.
In a new study published in JAMA Surgery, investigators reported that Roux-en-Y gastric bypass maintained significant differences from lifestyle and medical management in outcomes after 5-year in obese adults with type 2 diabetes, but with diminishing effectiveness.
Antipsychotic drugs cause severe side effects in individuals with schizophrenia, bipolar disorder, and autism-spectrum disorders. Now, scientists at the UNC School of Medicine and UC San Francisco (UCSF) have solved the first high-resolution crystal structure of the dopamine 2 receptor (DRD2) bound to the antipsychotic drug risperidone, yielding a long-awaited tool for drug developers, psychiatrists, and neuroscientists.