All news from Anaesthesiology

Earlier Exposures Cause Immune Response in Pediatric ARI

The suite of genes early-response cells was defined by factors such as age and previous exposures to viruses, according to a study by the Perelman School of Medicine at the University of Pennsylvania and Children's Hospital of Philadelphia (CHOP). Better understanding how early infections influence long-term immune response has implications for the diagnosis and treatment of young patients who suffer from acute respiratory tract infections.

Post-Surgery: Black Children Face Greater Risk of Death

A recent study, Race, Preoperative Risk Factors, and Death After Surgery, you have found that black children are more than twice as likely to die following surgery than white children and describe race-specific models to predict surgical outcomes . The study findings will be published online in the February 2018 issue of Pediatrics

Observed Harms Compared with Expected Mortality Benefit in LCS

In a new study published in JAMA Internal Medicine, the high rate of false-positive results identified in the VHA’s LCS demonstration project has caused concern about whether lung cancer screening (LCS) should be implemented in the population. By re-examining the data, researchers found that the high false-positive rate results in amore concerning harm-to-benefit ratio for those eligible persons at lower LC risk, but a much better harm-to benefit ratio for high-risk patients.

A Breakthrough that could Lead to Better Antipsychotic Therapy

Antipsychotic drugs cause severe side effects in individuals with schizophrenia, bipolar disorder, and autism-spectrum disorders. Now, scientists at the UNC School of Medicine and UC San Francisco (UCSF) have solved the first high-resolution crystal structure of the dopamine 2 receptor (DRD2) bound to the antipsychotic drug risperidone, yielding a long-awaited tool for drug developers, psychiatrists, and neuroscientists.