In the new research published today in Cancer Cell, researchers have figured out a way to prevent MYB, one of the most potent cancer-aiding proteins, from activating genes in AML, an aggressive form of leukaemia. Tested in mice, the new method resulted in dramatic cancer reduction and no harm to healthy cells. This could lead to a new therapy for AML and possibly other cancers.
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The students in the School of Health Professions at the University of Plymouth, in collaboration with a national network of healthcare professionals, worked in the research. Stroke and brain injury patients are being guided by the best choice of digital help.
Analysing big data to predict men's risk of side effects could help personalize radiotherapy treatment for prostate cancer, according to new research presented at the National Cancer Research Institute's (NCRI) Cancer Conference in Liverpool.
New research published in the Journal of Urban Health has analyzed crime data in Philadelphia for 10 years and found that rates of violent crime and disorderly conduct are higher when the weather is warmer and more pleasant, even rising sharply during warmer-than-typical winter days.
Virotherapy capable of destroying tumor cells and activating anti-tumor immune reactions, and the use of engineered hematopoietic stem cells (HSCs) to deliver replacement genes that have the potential to cure blood diseases are among the key areas of gene therapy being advanced by German researchers and highlighted in a special issue of Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The issue is available free on the Human Gene Therapy website.
Alzheimer's disease begins before the signs of memory loss, so some recent scientific efforts have focused on recognizing the earliest signs that portend disease onset. Those telltale signs, called biomarkers , would enable patients to receive treatment for Alzheimer's sooner. So, the National Institutes of Health called for research proposals to find new ways to diagnose Alzheimer's disease and predict its progression.
According to new study findings published in the JAMA Intern Medicine, multivariable analyses that include the risk factors suggest that the variations in life expectancy are largely explained by behavioural and metabolic risk factors, with socioeconomic and race/ethnicity factors no longer being statistically significant.
For families in the U.S., the costs of high-quality child care are exorbitant, especially for those with children under age five. A new policy proposal, "Public Investments in Child Care," by Dartmouth Associate Professor of Economics Elizabeth Cascio, finds that current federal child care tax policies are not benefiting the families most burdened by childcare costs. Therefore, Cascio outlines a new policy that could replace the current federal child care tax policies. The research examines child care for children ages 0-12 years, with a focus on 0-4 years.
Salk researchers have discovered how to curb the growth of cancer cells by blocking the cells' access to certain nutrients. The approach, detailed in Nature, took advantage of knowledge on how healthy cells use a 24-hour cycle to regulate the production of nutrients and was tested on glioblastoma brain tumors in mice.
Chemicals that could potentially cause asthma through an immune reaction could be better identified with human cell- and computer-based test methods, according to a new research paper co-authored by the Physicians Committee's Kristie Sullivan, M.P.H., in Applied In Vitro Toxicology.
A new study published in the Annals of Family Medicine has reported that researchers explored junior and senior family physicians' experiences with and attitudes toward managing medical requests from nonpatients. Senior physicians were more confident with handling medical questions from family or friends. While, junior physicians found this process more difficult, and they were more cautious about avoiding the potential consequences and pitfalls, according to the study.
When expectant mothers consume sufficient amounts of the nutrient choline during pregnancy, their offspring gain enduring cognitive benefits, a new Cornell University study suggests.