A study from the Oregon State University scientists have established a nanomedicine platform for cancer that can help doctors know which tissue to cut out as well as kill any malignant cells that can't be surgically removed. These findings by researchers in the OSU/OHSU College of Pharmacy and OSU College of Veterinary Medicine were published in Theranostics.
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Researchers developed a single blood test, CancerSEEK, that screens for eight common cancer types and helps identify the location of cancer. The test is a unique non-invasive, multianalyte test that simultaneously evaluates levels of eight cancer proteins and the presence of cancer gene mutations from circulating DNA in the blood. The study findings published in Science.
For the first time, researchers have described atom-by-atom changes in a family of proteins linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia and degenerative diseases of muscle and bone. The study findings appeared in the journal Molecular Cell.
A study showed that Klotho proteins play an important role in the regulation of longevity and metabolism. In a recent study, researchers revealed the three-dimensional structure of one of these proteins, beta-Klotho, illuminating its intricate mechanism and therapeutic potential. The study published in Nature.
According to a new University of Maryland-led study released, flu transmission reveals that we may pass the flu to others just by breathing. While, people commonly believe that they can catch the flu by exposure to droplets from an infected person's coughs or sneezes or by touching contaminated surfaces.
Researchers at Penn State are using new statistical analysis methods to compare how we observe infants develop new skills with the unseen changes in electrical activity in the brain, or electroencephalography ( EEG ) power. They found that most babies appear to learn new skills in irregular bursts, while their EEG power grows steadily behind the scenes. The study was published in the Child Development
In this study, researchers have developed the first map of gene regulation in human neurogenesis, the process by which neural stem cells turn into brain cells and the cerebral cortex expands in size. The scientists identified factors that govern the growth of our brains. Brain development is guided by the expression of genes in certain brain regions or cell types, as well as during specific time frames.
According to this study, researchers declared in a pre-anaesthetic clinic (PAC), as in any clinical service, patient satisfaction is important. This may be influenced by many factors. The main factor adversely affecting patient satisfaction is time spent in the clinic. Total time spent in PAC can be split into two parts: waiting time and consultation time, which have been defined. Patients needing emergency surgery are also not seen as they are assessed in the operating theatre itself.
A Food and Drug Administration (FDA) advisory panel voted against recommending ciprofloxacin dispersion for inhalation, to treat adult non-cystic fibrosis bronchiectasis (NCFBE) patients who have chronic lung infections with Pseudomonas aeruginosa.
In a study published in Nature, scientists have found that the role of Myc (generation of new blood cells in bone marrow and role in cancer) is determined by a distant section of DNA that contains a cluster of gene enhancers. In certain blood cancer cells, this cluster has been altered, which affects Myc activity and thereby accelerates cancer growth and affects how cancer responds to chemotherapy. This cluster of enhancers might, therefore, be a suitable target for the treatment of blood cancer.
Researchers investigated the effect of indole exposure on Salmonella virulence and infection. A competitive index test was used to compare the fitness of indole-treated and non-treated Salmonella in infecting mice. In addition, the effect of indole on other Salmonella functions important for infection such as motility, invasion, intracellular survival, and SPI-1 gene expression was also investigated.