According to results from an open-label randomized trial, extended-pulsed fidaxomicin, delivering 20 doses over a longer time period after initial daily dosing, appears superior to standard-dose vancomycin for sustained cure of Clostridium difficile infection in patients age 60 or older.The study results was published in the Lancet Infectious Diseases.
Greenwood Genetic Center (GGC) in collaboration with scientists from Canada have identified unique epigenetic signatures for nine neurodevelopmental disorders lending to a better method of diagnosis for disorders with much clinical overlap. The epigenetic signatures were developed through methylation analysis and were reported in The American Journal of Human Genetics .
On average, former elite athletes survive longer than their brothers. In addition, their self-rated health and health-related habits are better in comparison to their brothers at an older age. This was clarified by Master of Health Sciences (Sports and Exercise Medicine) Titta Kontro from the Faculty of Sport and Health Sciences at the University of Jyväskylä. The study included in total 900 former elite athletes and their brothers.
A major review by UNSW Sydney medical researchers has identified strong evidence that a virus called Enterovirus D68 is the cause of a mystery polio-like illness that has paralyzed children in the US, Canada, and Europe.
A researcher examined the study from an Optimal patient positioning is perceived as an essential factor to increase the success of performing neuraxial blockade. A main aim of this study was to evaluate the benefit of using a visual image in addition to verbal instructions to optimize positioning for spinal block. Patient positioning can also independently predict the success of performing neuraxial anesthesia.
A new study published in the Annals of Emergency Medicine has shown that six months after visiting the emergency room (ER), seniors were 14% more likely to have acquired a disability (an inability to independently bathe, dress, climb down a flight of stairs, shop, manage finances or carry a package, for instance) than older adults of the same age, with a similar illness, who did not end up in the ER.
The recently approved combination of dolutegravir and rilpivirine is effective for maintaining virological suppression in adults with HIV-1, according to results from the SWORD-1 and SWORD-2 noninferiority studies.
According to results from the CARE-ROP study, Low doses of anti-VEGF therapy with ranibizumab are effective in infants with retinopathy of prematurity (ROP). The study findings were published in the JAMA Pediatrics
According to this study, Hisayama Study is an ongoing, population-based epidemiologic study in the town of Hisayama, which is in a suburb of the Fukuoka metropolitan area on Kyushu Island, Japan. Whether the intake of eicosapentaenoic acid (EPA) or arachidonic acid (AA) affects the risk of cancer remains unclear, and the association between the serum EPA:AA ratio and cancer risk has not been fully evaluated in general populations.
New research published in Schizophrenia Bulletin has reported that oral clozapine and olanzapine long-acting injection (LAI) emerged as the most effective treatments for preventing hospitalization among patients with chronic and first-episode schizophrenia in a large, long-term comparative effectiveness study.
A study led by researchers at the University of Washington School of Medicine in Seattle shows that, in preterm animal models, inflammation due to infection can disrupt the activity of genes that are crucial for normal development of the heart. The study findings were published in the American Journal of Obstetrics & Gynecology .
A study demonstrates that researchers have been approved for adjuvant use in the treatment of melanoma, nivolumab is likely to become the new standard of care in this setting. It is now indicted for adjuvant treatment of patients who have undergone complete resection and who have lymph node involvement or metastatic disease. The study published in the New England Journal of Medicine.