A recently demonstrated randomized trial compared APRV versus the current standard of care, low-tidal-volume ventilation (LTV). Although many consider APRV to be a "rescue mode" for refractory hypoxemia, others argue that it minimizes ventilator-induced lung injury and maintain that APRV should be the primary mode of ventilation for patients with ARDS. This study was published in The American Journal of Respiratory and Critical Care Medicine.
Accepting organs from HIV-positive donors for HIV-positive patients on the transplant waiting list could help ease the organ shortage, Dr. Hilton and her team note in their report. This would likely result in one or two organ donations from HIV-positive people per year, the researcher said. The study findings was published in the Clinical Kidney Journal
A new study published in Nature Medicine reported a surprising role of immune system in the aftermath of heart attacks. The findings revealed a new potential therapeutic opportunity to prevent heart attacks from progressing to heart failure in patients.
A new Research using a new skill, Navy Aerospace Medical Institute (NAMI), a detachment of Navy Medicine Operational Training Center (NMOTC) investigated that could potentially become an early-warning signal to military pilots who are experiencing inflight physiologic events such as hypoxia.The senior medical officer of Naval Aviation Schools Command (NASC), who coordinates all NAMI research, is working with new Electroencephalogram (EEG) technology for use in hypoxia detection.
According to a consensus statement from the European Academy of Pediatrics and the European Childhood Obesity Group, In the past 25 years, obesity rates have climbed rapidly among European children and teens. The study was published in the Acta Paediatrica. Roughly one in five kids and teens in Europe are overweight or obese, according to a 2017 World Health Organization study, the authors note.
Researchers at Stanford established a direction by making a detailed cell-by-cell gene blueprint of the fruit fly's olfactory neurons. Scientists have been working to zoom in and identify how brain circuits form so they can learn to rewire troublemaking neurons. The human nervous system is like a complex circuit board. When wires cross or circuits malfunction, conditions such as schizophrenia or bipolar disorder can arise. Their study has been published in Cell.
A sampling of U.S. emergency department records confirms that sticking anything smaller than your elbow in your ear is a good way to puncture an eardrum. About 66% of patients treated for traumatic tympanic membrane perforations had hurt themselves by sticking “instruments,” in their ears, and nearly half of these cases involved cotton-tipped swabs. This published in JAMA Otolaryngology Head & Neck Surgery.
Guizhi Zhu, from the NIBIB Laboratory of Molecular Imaging and Nanomedicine (LOMIN) and his colleagues have created what they call a "self-assembling, intertwining DNA-RNA nanocapsule loaded with tumor neoantigens." They describe it as a synergistic vaccine because the components work together to stimulate and enhance an immune attack against a tumor.The study was published in the Nature Communications.
According to a forensic investigator Mr Huang, IKA® UTTD resolves a most important problem in forensic identification field. The IKA® UTTD control avoids cross-contamination during forensic toxic sample processing and thus enhances the processing efficiency.
The Scientists at the Center for Self-Assembly and Complexity, within the Institute for Basic Science (IBS), developed a hydrogel to fight rheumatoid arthritis and other diseases. Published in Advanced Materials, this jelly-like material could be used to absorb extra fluids in swelling joints and release drugs.
Scientists have examined deep into the heart of a key protein used in drug design and discovered dynamic structural features that may lead to new ways to target diseases. A protein called A2A adenosine receptor (A2aAR), is a member of the G-protein-coupled receptor (GPCR) family, which are the targets of roughly 40 percent of all approved pharmaceuticals.
The new, more detailed image of A2aAR's signaling mechanism reveals key parts of its inner workings, including an amino acid that acts like a "toggle switch" to control signaling across the cell membrane. This study was published in the journal Cell.
According to a study published in the Journal of Crohn's and Colitis, steroid therapy is associated with an increased risk of venous thromboembolic events in patients with inflammatory bowel disease (IBD), but biological therapy is not . The risk of venous thromboembolism (VTE) is 1.5- to 3-fold higher in IBD patients, compared with non-IBD controls, with most events occurring during acute flare-ups of the disease.