Scientists developed an innovative approach to deliver drugs, via a micro-needle patch, with drugs that are known to turn energy-storing white fat into energy-burning brown fat. It reduced weight gain in mice on a high-fat diet and their fat mass by more than 30% over four weeks. The findings published in the journal Small Methods.
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Men with Peyronie's disease (PD) are at increased risk of malignancy including cancer of the stomach and testis, suggesting they may need additional surveillance after diagnosis and treatment for PD, say researchers from Baylor College of Medicine in Houston.
More than a third of patients with HIV infection fail to get hepatitis B virus (HBV) vaccination, despite a longstanding recommendation, report researchers from the Centers for Disease Control and Prevention (CDC) in Atlanta.
A new study published in the issue of the journal Clinical Gastroenterology and Hepatology has shown that monitoring patients treated with infliximab prior to the loss of patient response to the drug is associated with better long-term outcomes than monitoring the drug only after it loses efficacy. The team's retrospective study could set the stage for a change in the standard clinical approach to IBD.
Pfizer's bivalent meningococcal B vaccine targeting factor H-binding protein (MenB-FHbp, Trumenba) elicits bactericidal responses against diverse meningococcal B strains after the second and third doses in adolescents and young adults, according to two phase 3 studies published online in The New England Journal of Medicine.
A new study revealed that German GPs were beginning to delegate tasks to non-physicians and should extend delegated tasks to their practice staff, but the implementation of task shifting depends on different aspects, such as legal requirements, adequate payment and qualified staff.
A member of the Indian parliament wrote a letter to Prime Minister Narendra Modi, urging him to cap the prices of 20 medical devices to bring down hospitalization costs and make healthcare more affordable.
Peter A Kahn, MD, Yale School of Medicine, New Haven, Connecticut, and colleagues suggests, Glucagon is under used for treating severe hypoglycemia in both emergency and outpatient settings.Findings from an analysis of data on glucagon administration by emergency personnel and glucagon prescribing under Medicare. The study findings were published in the Annals of Internal Medicine.
Researchers find a way to capture detailed information on human sleep cycles over long periods of time while individuals slumber at home in their usual way. According to the researchers, the findings represent a major breakthrough in sleep as for the first time it was possible to objectively capture the real-life sleep habits and sleep quality of large numbers of people. The study is published in Current Biology.
HIV-positive individuals have lower neuropsychological test scores and smaller brain volumes than HIV-negative people, but the disadvantages of patients who receive combination antiretroviral therapy (CART), reporters. The study findings were published in the JAMA Neurology
Of every 100 Americans who drink (140 million), about 12 (16 million) are considered in need of treatment for an alcohol use disorder, and eight will become chemically dependent on alcohol. Of that eight, one will become addicted very early, even after the first drunken episode. The problem is, we do not yet have a way to predict who that one person will be.