According to study published in ACS Journal of Medicinal Chemistry, artificial sweeteners are used in diet drinks and foods but also could someday be used as treatments targeting carbonic anhydrase IX (CA IX), a protein associated with aggressive cancers. Although several drugs have been approved that target similar forms of CA, they aren't selective and may cause side effects, including vomiting and fatigue.
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A new type of gene therapy delivered using a virus could protect healthy tissues from the harmful side-effects of radiotherapy after cancer treatment, a new study reports.
A new type of gene therapy delivered using a virus could protect healthy tissues from the harmful side-effects of radiotherapy after cancer treatment, a new study reports. The study is published today (Wednesday) in the journal Science Translational Medicine, and was largely funded by the Wellcome Trust.
According to a new research, people who have undergone hip surgery with total hip arthroplasty often experience no difficulty in walking – but for some, mobility actually is impaired long after surgery. Researchers focused on how advanced motion analysis can lead to improvements for patients.
A new study reinforces earlier work suggesting that MRI scans are safe for patients with older devices, even if the MRI is focusing on the chest area.
Scientists at the Morgridge Institute for Research have discovered a new Achilles heel in the replication process of positive-strand RNA viruses, a class responsible for health threats such as Zika, polio, chikungunya and hepatitis C. The discovery points to a potentially valuable new target for broad-spectrum antivirals for positive-strand RNA viruses, which make up one-third of known viruses.
In new research, scientists have tested a new precision medicine approach –OncoTreat therapy— to treat metastatic pancreatic cancer. Using the new approach, the team studied the RNA; the tissue-specific copy of a cancer cell’s DNA, rather than the DNA itself. This will give a much more accurate picture of the genetic programs operating inside a tumor that enable its survival.
According to a new study, direct care experiences with transgender patients not only increases the confidence of medical providers in providing care, but more importantly provides the patient with a better experience.
Most people with lung disease carry mutations in one of the genes that build the proteins that form molecular motors inside cilia. A single misshapen piece of protein can make the whole machine grind to a halt. But a few people have errors in proteins that are not part of the motor. Researchers at Washington University School of Medicine in St. Louis report they have solved that puzzle: The nonmotor proteins are like factory workers who put the motor together. Mutations cause these proteins to assemble the motor incorrectly.
In a new study, the researhcers have found that BMAA, a toxin linked to several neurodegenerative diseases, is present in high concentrations during cyanobacteria blooms in Lake Winnipeg.
In a milestone achievement for better understanding the development and function of the human placenta, scientists have derived and grown trophoblast stem cells for the first time.
An estimated 39397 people were living with HIV in Nepal at the end of 2015. In the same year 1331 people were newly infected with HIV and there were 2263 AIDS-related deaths. Despite steady improvements, the global target to reach 90% treatment coverage is far from being accomplished, as only about 30% of people living with HIV in Nepal were enrolled in treatment.