All news from Anaesthesiology

Artificial Sweetener may Help Treat Aggressive Cancer with Less Side Effects

According to study published in ACS Journal of Medicinal Chemistry, artificial sweeteners are used in diet drinks and foods but also could someday be used as treatments targeting carbonic anhydrase IX (CA IX), a protein associated with aggressive cancers. Although several drugs have been approved that target similar forms of CA, they aren't selective and may cause side effects, including vomiting and fatigue.

Novel Approach to Treat Metastatic Pancreatic Cancer

In new research, scientists have tested a new precision medicine approach –OncoTreat therapy— to treat metastatic pancreatic cancer. Using the new approach, the team studied the RNA; the tissue-specific copy of a cancer cell’s DNA, rather than the DNA itself. This will give a much more accurate picture of the genetic programs operating inside a tumor that enable its survival.

Scientists Identified Molecular Roots of Genetic Lung Disorder

Most people with lung disease carry mutations in one of the genes that build the proteins that form molecular motors inside cilia. A single misshapen piece of protein can make the whole machine grind to a halt. But a few people have errors in proteins that are not part of the motor. Researchers at Washington University School of Medicine in St. Louis report they have solved that puzzle: The nonmotor proteins are like factory workers who put the motor together. Mutations cause these proteins to assemble the motor incorrectly.

Nepal HIVision 2020: National HIV Strategic plan at a glance

An estimated 39397 people were living with HIV in Nepal at the end of 2015. In the same year 1331 people were newly infected with HIV and there were 2263 AIDS-related deaths. Despite steady improvements, the global target to reach 90% treatment coverage is far from being accomplished, as only about 30% of people living with HIV in Nepal were enrolled in treatment.