All news from Anaesthesiology

Cardiotoxicity testing using In Vitro and In Vivo models

Renal and hepatotoxicity of diglycolic acid (DGA) has been described with in vitro cellular models as well as in vivo animal and human systems. The possibility of diglycolic acid (DGA) being toxic to other organs, such as the heart, has not been well investigated. A human case report identified the heart as a potential target organ of DGA, but an in-house in vivo rat study neither found gross nor microscopic pathological changes following repeated oral DGA exposure.

Plague: Are amoebae safe harbors?

Amoebae, single-celled organisms common in soil, water, and grade-school science classrooms, may play a key role in the survival and spread of deadly plague bacteria. New research shows that plague bacteria, Yersinia pestis, not only survive but thrive and replicate once ingested by an amoeba. The discovery could help scientists understand why plague outbreaks can smolder, stay dormant for years, and re-emerge with a vengeance.

Unsafe Habits Associated with Sleep-Related Infant Deaths

According to a report from the US Centers for Disease Control and Prevention, many parents still regularly risk their babies' lives as they put them to bed. Analyzing data from the states, the CDC found that parents continued to practice unsafe habits that have been associated with sleep-related infant deaths , including sudden infant death syndrome ( SIDS ).