All news from Anaesthesiology

Scientist Seek to Standardize Treatments for Childhood Rheumatic Diseases

Pediatric rheumatic diseases are a varied group of rare diseases including juvenile forms of arthritis, lupus, fibromyalgia, and other conditions. Currently, there is considerable variability in how patients with these diseases are treated in clinical practice, making it difficult to understand which therapies work best. A new study published in the journal Arthritis & Rheumatology examines recent efforts to address this challenge.

Novel Treatment for AML and Possibly Other Cancers

In the new research published today in Cancer Cell, researchers have figured out a way to prevent MYB, one of the most potent cancer-aiding proteins, from activating genes in AML, an aggressive form of leukaemia. Tested in mice, the new method resulted in dramatic cancer reduction and no harm to healthy cells. This could lead to a new therapy for AML and possibly other cancers.

Human gene therapy: Advances in Cancer and Blood Disorders

Virotherapy capable of destroying tumor cells and activating anti-tumor immune reactions, and the use of engineered hematopoietic stem cells (HSCs) to deliver replacement genes that have the potential to cure blood diseases are among the key areas of gene therapy being advanced by German researchers and highlighted in a special issue of Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The issue is available free on the Human Gene Therapy website.

Quest MRI to Identify Earliest Signs of Alzheimer's Disease in Mice

Alzheimer's disease begins before the signs of memory loss, so some recent scientific efforts have focused on recognizing the earliest signs that portend disease onset. Those telltale signs, called biomarkers , would enable patients to receive treatment for Alzheimer's sooner. So, the National Institutes of Health called for research proposals to find new ways to diagnose Alzheimer's disease and predict its progression.

Predictors of Life Expectancy Inequality

According to new study findings published in the JAMA Intern Medicine, multivariable analyses that include the risk factors suggest that the variations in life expectancy are largely explained by behavioural and metabolic risk factors, with socioeconomic and race/ethnicity factors no longer being statistically significant.

Reforms to improve access to affordable, high quality child care

For families in the U.S., the costs of high-quality child care are exorbitant, especially for those with children under age five. A new policy proposal, "Public Investments in Child Care," by Dartmouth Associate Professor of Economics Elizabeth Cascio, finds that current federal child care tax policies are not benefiting the families most burdened by childcare costs. Therefore, Cascio outlines a new policy that could replace the current federal child care tax policies. The research examines child care for children ages 0-12 years, with a focus on 0-4 years.

Physicians Face Complexity When Managing Medical Requests from Nonpatients

A new study published in the Annals of Family Medicine has reported that researchers explored junior and senior family physicians' experiences with and attitudes toward managing medical requests from nonpatients. Senior physicians were more confident with handling medical questions from family or friends. While, junior physicians found this process more difficult, and they were more cautious about avoiding the potential consequences and pitfalls, according to the study.