All news from Anaesthesiology

New Hope for Patients Awaiting Corneal Transplants

Jonathan Lass of Case Western Reserve University School of Medicine has found that corneal donor tissue can be safely stored for 11 days before transplantation surgery to correct eye problems in people with diseases of the cornea. This is four days longer than the current conventional maximum of seven days in the United States. The findings were published in the  JAMA Ophthalmology .

An Older Person's Emergency Case Often Signals To Serious Issue

In this study, researchers found Six months after visiting the ER, seniors were 14 percent more likely to have acquired a disability, an inability to independently bathe, dress, climb down a flight of stairs, shop, manage finances, for instance than older adults of the same age, with a similar illness and does not end up with ER. These older adults weren't admitted to the hospital from the ER; they returned home after their visits, as do about two-thirds of seniors who go to ERs, nationally. This study got published in the Annals of Emergency Medicine.

Nanosponges Offer Promising Solution For Sepsis

According to researchers from the University of California San Diego have established macrophage "nanosponges" that can safely absorb and remove molecules from the bloodstream that are known to trigger sepsis. These macrophage nanosponges, which are nanoparticles cloaked in the cell membranes of macrophages, have so far improved survival rates in mice with sepsis. This study has been published in Proceedings of the National Academy of Sciences.

Association Between Place Of Residence And Heart Failure Risk

According to new study, researchers have conducted comparative study i.e., census tract data on socioeconomic deprivation, a collection of neighborhood-level variables of wealth, education, occupation and housing patterns and heart failure rates among 27,078 middle-aged participants from South-eastern states. This study is published in American Heart Association journal, Circulation: Cardiovascular Quality and Outcomes.

Newly Solved Glucagon Receptor Structure Offers Drug Design

According to new study, scientists at SIMM determined the crystal structure of GCGR in complex with a glucagon analogue and partial agonist NNC1702. This structure reveals, for the first time, the molecular details of a class B GPCR binding to its peptide ligand at high resolution and unexpectedly discloses the structural complexity that governs receptor activation, so significantly expanding the understanding of class B GPCR signal transduction. The study was published in Nature.