All news from Anaesthesiology

Stress Linked to Early Development of Pancreatic Cancer

A new study published in the journal Cancer Cell has showed that stress accelerates the development of pancreatic cancer by triggering the release of "fight-or-flight" hormones. Beta-blockers–commonly used medications that inhibit these hormones–were found to increase survival in a mouse model of the disease. An additional analysis of patients with advanced pancreatic cancer revealed that those who were taking selective beta-blockers lived approximately two-thirds longer than those who were not taking the medications.

New Deep-Learning based Hematological Human Aging Clock Developed

In a research paper published in The Journal of Gerontology, the authors present a novel deep-learning based hematological human aging clock, a biomarker that predicts the biological age of individual patients. The developed model predicts the age better than models tailored to the specific populations highlighting the differences of subregion-specific patterns of aging. In addition, the developed clocks were shown to be a better predictor of all-cause mortality than chronological age.

Alzheimer’s Drug Turns Back a Cellular Clock

The experimental drug J147 is something of a modern elixir of life; it's been shown to treat Alzheimer's disease and reverse aging in mice and is almost ready for clinical trials in humans. A new study, published in the journal Aging Cellreports that the drug, J147, binds to a protein found in mitochondria, the energy-generating powerhouses of cells. In turn, the study showed, it makes aging cells, mice and flies appear more youthful.

Specific Brain Circuit Controls Social Behavior

A new study published in Biological Psychiatry  has identified a key brain region of the neural circuit that controls social behavior. Increasing the activity of this region, called the habenula, led to social problems in rodents, whereas decreasing activity of the region prevented social problems. The improved understanding of altered brain function could help develop new targeted therapeutics for autism spectrum disorder.

X-Ray Navigation In Space Was Established By NASA

According to this study, researchers found a team of NASA engineers has demonstrated fully autonomous X-ray navigation in space, a capability that could revolutionize NASA's ability in the future to pilot robotic spacecraft to the far reaches of the solar system and beyond. The team carried out with an experiment called Station Explorer for X-ray Timing and Navigation Technology. 

Development of Gene Regulation Map in Human Neurogenesis

UCLA researchers have developed the first map of gene regulation in human neurogenesis, the process by which neural stem cells turn into brain cells and the cerebral cortex expands in size. The scientists identified factors that govern the growth of our brains and, in some cases, set the stage for several brain disorders that appear later in life.