All news from Anaesthesiology
According to a consensus statement from the European Academy of Pediatrics and the European Childhood Obesity Group, In the past 25 years, obesity rates have climbed rapidly among European children and teens. The study was published in the Acta Paediatrica. Roughly one in five kids and teens in Europe are overweight or obese, according to a 2017 World Health Organization study, the authors note.
Researchers at Stanford established a direction by making a detailed cell-by-cell gene blueprint of the fruit fly's olfactory neurons. Scientists have been working to zoom in and identify how brain circuits form so they can learn to rewire troublemaking neurons. The human nervous system is like a complex circuit board. When wires cross or circuits malfunction, conditions such as schizophrenia or bipolar disorder can arise. Their study has been published in Cell.
A sampling of U.S. emergency department records confirms that sticking anything smaller than your elbow in your ear is a good way to puncture an eardrum. About 66% of patients treated for traumatic tympanic membrane perforations had hurt themselves by sticking “instruments,” in their ears, and nearly half of these cases involved cotton-tipped swabs. This published in JAMA Otolaryngology Head & Neck Surgery.
Guizhi Zhu, from the NIBIB Laboratory of Molecular Imaging and Nanomedicine (LOMIN) and his colleagues have created what they call a "self-assembling, intertwining DNA-RNA nanocapsule loaded with tumor neoantigens." They describe it as a synergistic vaccine because the components work together to stimulate and enhance an immune attack against a tumor.The study was published in the Nature Communications.
According to a forensic investigator Mr Huang, IKA® UTTD resolves a most important problem in forensic identification field. The IKA® UTTD control avoids cross-contamination during forensic toxic sample processing and thus enhances the processing efficiency.
The Scientists at the Center for Self-Assembly and Complexity, within the Institute for Basic Science (IBS), developed a hydrogel to fight rheumatoid arthritis and other diseases. Published in Advanced Materials, this jelly-like material could be used to absorb extra fluids in swelling joints and release drugs.
Scientists have examined deep into the heart of a key protein used in drug design and discovered dynamic structural features that may lead to new ways to target diseases. A protein called A2A adenosine receptor (A2aAR), is a member of the G-protein-coupled receptor (GPCR) family, which are the targets of roughly 40 percent of all approved pharmaceuticals.
The new, more detailed image of A2aAR's signaling mechanism reveals key parts of its inner workings, including an amino acid that acts like a "toggle switch" to control signaling across the cell membrane. This study was published in the journal Cell.
According to a study published in the Journal of Crohn's and Colitis, steroid therapy is associated with an increased risk of venous thromboembolic events in patients with inflammatory bowel disease (IBD), but biological therapy is not . The risk of venous thromboembolism (VTE) is 1.5- to 3-fold higher in IBD patients, compared with non-IBD controls, with most events occurring during acute flare-ups of the disease.
The evidence is clear: Cervical cancer is best treated with brachytherapy, a form of radiation therapy. Yet the use of this potentially lifesaving treatment has been declining, and a new study published in International Journal of Radiation Oncology may explain why. The study determined that eventhough, Medicare costs hospitals more than twice as much to provide brachytherapy as it does to provide external-beam radiation, the reimbursement doesn't reflect that.
New research shows that in a mouse model of childhood absence epilepsy, brain activity is perturbed between seizures. The researchers speculate that this could underlie cognitive problems of the disease, which can persist despite treatment of seizures, according to research published today in The Journal of Physiology.
In a new study presented at the meeting of the American Society of Haematology (ASH) conference, the researchers suggested that forging AI (Artificial intelligence) with genomics will push precision medicine forward in blood cancer and lead to new insights and discoveries.
The drug, called pentyl pantothenamide , is able to stop the growth of E.coli but not completely kill the bacterium, so it was never taken into clinical use.The study findings were published in the journal Biochemistry , open up the possibility of designing new drugs that use the same means to attack E. coli, but in a more effective way.