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Genetics Of Autism Spectrum Disorders: Mice Provide Better Insights

Research shows that CHD8 gene mutation is associated with some cases of human autism. In mice cortex with this mutation caused increased brain size hence giving an insight into genetic causes of autism spectrum disorders.

Although the absolute causes are not clear, many genetic and environmental factors enhance the probability of autism spectrum disorder. "For years, the targets of drug discovery and treatment have been based on an unknown black box of what's happening in the brain," said Nord (assistant professor of neurobiology).